INT181059

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Context Info
Confidence 0.25
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 0.98
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclease activity (Rnase1)
Anatomy Link Frequency
brain 1
Rnase1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 104 75.60 Quite High
fibrosis 11 73.28 Quite High
chemokine 13 55.56 Quite High
medulla 5 48.20 Quite Low
Inflammatory response 31 44.40 Quite Low
alcohol 2 43.36 Quite Low
cytokine 11 5.00 Very Low Very Low Very Low
agonist 11 5.00 Very Low Very Low Very Low
Glutamate receptor 6 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 166 100.00 Very High Very High Very High
Wound Healing 10 80.88 Quite High
Vibrio Infection 3 78.76 Quite High
INFLAMMATION 133 75.60 Quite High
Fibrosis 14 73.28 Quite High
Pressure And Volume Under Development 2 56.96 Quite High
Alzheimer's Dementia 21 50.00 Quite Low
Fragile X Syndrome 21 50.00 Quite Low
Body Weight 2 44.20 Quite Low
Targeted Disruption 67 24.40 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RNA isolation and RNase protection assay
Gene_expression (protection) of RNase
1) Confidence 0.25 Published 2010 Journal The Journal of Cell Biology Section Body Doc Link PMC2845079 Disease Relevance 0.08 Pain Relevance 0
For complete RNase digestion, recombinant RNase A and T1 (Ambion) were added to mouse brain lysates to a final concentration of 20 ug/ml and 10,000 U/ml respectively.
Gene_expression (digestion) of RNase in brain
2) Confidence 0.24 Published 2009 Journal PLoS Genetics Section Body Doc Link PMC2779495 Disease Relevance 0.06 Pain Relevance 0
Measurements of Nipbl levels by RNase protection were made according to standard methods.
Gene_expression (protection) of RNase
3) Confidence 0.21 Published 2009 Journal PLoS Genetics Section Body Doc Link PMC2730539 Disease Relevance 0 Pain Relevance 0
1, which we have previously shown to be differentially expressed in wild-type versus PU.1 null wounds in RNase protection assays [6], and the same may be true for several other classes of genes expressed at low copy number.
Gene_expression (expressed) of RNase associated with injury
4) Confidence 0.17 Published 2005 Journal Genome Biol Section Body Doc Link PMC549066 Disease Relevance 0.85 Pain Relevance 0.19
Despite the presence of an RNase-protected, G-rich sequence, APP mRNA might not associate directly with FMRP.
Gene_expression (presence) of RNase-protected
5) Confidence 0.13 Published 2007 Journal PLoS Biology Section Body Doc Link PMC1808499 Disease Relevance 0 Pain Relevance 0

General Comments

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