INT181076

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Context Info
Confidence 0.11
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.47
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

kinase activity (Map4k4, Mapk8) cytoplasm (Map4k4, Mapk8) cytosol (Mapk8)
signal transduction (Mapk8) mitochondrion (Mapk8) nucleus (Mapk8)
Map4k4 (Mus musculus)
Mapk8 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 2 97.60 Very High Very High Very High
Inflammation 75 61.08 Quite High
Inflammatory response 26 5.00 Very Low Very Low Very Low
chemokine 13 5.00 Very Low Very Low Very Low
fibrosis 10 5.00 Very Low Very Low Very Low
local anesthetic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 2 98.24 Very High Very High Very High
Injury 161 79.60 Quite High
INFLAMMATION 101 61.08 Quite High
Wound Healing 10 50.00 Quite Low
Cancer 3 39.92 Quite Low
Fibrosis 12 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Fibromyalgia 3 5.00 Very Low Very Low Very Low
Keloid Scars 2 5.00 Very Low Very Low Very Low
Eczema 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Map4k4, a member of the serine/threonine protein kinase family that activates the JNK and MAPK signaling pathways in response to stress signals, cytokines and growth factors [16], is a member of the early effector cluster.
Map4k4 Positive_regulation (activates) of JNK associated with stress and cytokine
1) Confidence 0.11 Published 2005 Journal Genome Biol Section Body Doc Link PMC549066 Disease Relevance 0.47 Pain Relevance 0.11

General Comments

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