INT181097

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Context Info
Confidence 0.13
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.95
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

kinase activity (Chka) cytoplasm (Chka)
Anatomy Link Frequency
muscle 1
Chka (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 5 95.92 Very High Very High Very High
Inflammation 17 51.32 Quite High
iatrogenic 3 39.92 Quite Low
aspirin 25 38.40 Quite Low
Pain 3 17.12 Low Low
agonist 3 13.60 Low Low
Spinal cord 1 6.48 Low Low
anesthesia 5 5.00 Very Low Very Low Very Low
Versed 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 76 99.48 Very High Very High Very High
Carcinoma 32 99.44 Very High Very High Very High
Cancer 108 97.96 Very High Very High Very High
Disease 65 96.48 Very High Very High Very High
Necrosis 2 93.88 High High
Myositis 51 90.40 High High
Polymyositis 6 85.80 High High
Dermatomyositis 5 85.24 High High
Adhesions 10 79.24 Quite High
Metastasis 6 77.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Current disease status of patients was assessed using the standard clinical tools available in the outpatient setting (that is, the results of "extended" manual muscle testing [MMT] [22] and circulating creatinine kinase [CK] and C-reactive protein [CRP] levels).
Regulation (circulating) of CK in muscle associated with disease
1) Confidence 0.13 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526646 Disease Relevance 1.27 Pain Relevance 0.12
Another explanation could be the heterogeneity of expression of markers such as CK and EpCAM in carcinoma cells.
Regulation (heterogeneity) of CK associated with carcinoma
2) Confidence 0.10 Published 2004 Journal Breast Cancer Res Section Body Doc Link PMC549166 Disease Relevance 0.59 Pain Relevance 0
However, on low dose collagen aggregometry, high response group showed higher LD and CK levels (P values = 0.009 and 0.028 respectively) (Fig. 1) than low response group.


Regulation (values) of CK
3) Confidence 0.06 Published 2010 Journal Korean Journal of Anesthesiology Section Body Doc Link PMC2872863 Disease Relevance 0.15 Pain Relevance 0
Major CK alterations observed in breast cancer could be reflected by the reduced or increased expression of individual CK, and by partial loss of the normal regulation of CK expression [45].
Regulation (alterations) of CK associated with breast cancer
4) Confidence 0.05 Published 2004 Journal Breast Cancer Res Section Body Doc Link PMC549166 Disease Relevance 0.94 Pain Relevance 0

General Comments

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