INT181099

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Context Info
Confidence 0.33
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.70
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Epcam)
Epcam (Mus musculus)
Pain Link Frequency Relevance Heat
Bioavailability 8 5.00 Very Low Very Low Very Low
cytokine 7 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 157 99.60 Very High Very High Very High
Adhesions 11 94.00 High High
Metastasis 6 92.36 High High
Breast Cancer 76 86.72 High High
Pressure And Volume Under Development 48 85.64 High High
Malignant Neoplastic Disease 4 85.32 High High
Necrosis 2 85.28 High High
Carcinoma 35 83.36 Quite High
Disease 36 47.80 Quite Low
Colon Cancer 2 38.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The epithelial–mesenchymal transition occurring in metastatic processes leads to a transient loss of EpCAM expression during the migratory and early postmigratory period [40].
Negative_regulation (loss) of Gene_expression (expression) of EpCAM
1) Confidence 0.33 Published 2004 Journal Breast Cancer Res Section Body Doc Link PMC549166 Disease Relevance 1.08 Pain Relevance 0
We agree that Ficoll processing might eliminate cell clusters or aggregates, leading to the preferential loss of EpCAM-expressing cells.
Negative_regulation (loss) of Gene_expression (expressing) of EpCAM
2) Confidence 0.33 Published 2004 Journal Breast Cancer Res Section Body Doc Link PMC549166 Disease Relevance 0.67 Pain Relevance 0
This trifunctionality leads to effective destruction of EpCAM-positive tumour cells even at antibody concentrations in the pg ml?
Negative_regulation (effective) of Gene_expression (destruction) of EpCAM associated with cancer
3) Confidence 0.33 Published 2010 Journal British Journal of Clinical Pharmacology Section Body Doc Link PMC2878603 Disease Relevance 0.95 Pain Relevance 0

General Comments

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