INT181125

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Context Info
Confidence 0.59
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.14
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Raf1) signal transduction (Raf1) plasma membrane (Raf1)
cytoskeleton organization (Raf1) kinase activity (Raf1) cytoplasm (Raf1)
Anatomy Link Frequency
mononuclear cells 1
Raf1 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 2 99.84 Very High Very High Very High
Kinase C 15 9.28 Low Low
Inflammation 12 5.00 Very Low Very Low Very Low
adenocard 5 5.00 Very Low Very Low Very Low
Bioavailability 4 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 55 97.84 Very High Very High Very High
Immunization 13 88.60 High High
Thymoma 1 84.08 Quite High
Disease 33 81.52 Quite High
Solid Tumor 4 74.56 Quite High
Apoptosis 5 73.04 Quite High
Adenocarcinoma 1 50.28 Quite High
Sprains And Strains 32 50.00 Quite Low
Adenoma 7 50.00 Quite Low
Toxicity 7 41.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Construction of a C-Raf overexpressing EL-4 cell line
Transcription (Construction) of C-Raf
1) Confidence 0.59 Published 2005 Journal BMC Cancer Section Body Doc Link PMC549196 Disease Relevance 0.39 Pain Relevance 0.18
In a phase I trial, changes in the expression of c-raf1 mRNA were assessed in peripheral blood mononuclear cells, collected from patients with advanced cancers treated with ISIS 5132.
Transcription (expression) of c-raf1 in mononuclear cells associated with cancer
2) Confidence 0.52 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733095 Disease Relevance 0.75 Pain Relevance 0

General Comments

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