INT181179

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Context Info
Confidence 0.43
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 7
Disease Relevance 7.06
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural constituent of ribosome (CYLD) ribosome (CYLD) intracellular (CYLD)
cytoplasm (CYLD) cytosol (CYLD) peptidase activity (CYLD)
CYLD (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory mediators 5 97.80 Very High Very High Very High
cytokine 19 95.76 Very High Very High Very High
Inflammation 27 94.40 High High
headache 3 87.84 High High
Catecholamine 1 23.00 Low Low
cINOD 9 5.00 Very Low Very Low Very Low
tolerance 7 5.00 Very Low Very Low Very Low
psoriasis 4 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
carpal tunnel syndrome 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Short Bowel Syndrome 38 100.00 Very High Very High Very High
Sick Building Syndrome 19 100.00 Very High Very High Very High
Skin Cancer 12 100.00 Very High Very High Very High
Cancer 52 99.66 Very High Very High Very High
Stress 11 98.04 Very High Very High Very High
INFLAMMATION 37 97.40 Very High Very High Very High
Cholesteatoma 240 97.32 Very High Very High Very High
Rheumatoid Arthritis 96 96.44 Very High Very High Very High
Pruritus 2 94.16 High High
Hypersensitivity 10 92.08 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
At this point, CYLD binds to NF-?
CYLD Binding (binds) of
1) Confidence 0.43 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2858283 Disease Relevance 0.48 Pain Relevance 0.03
B activation accompanied by loss of CYLD may be an important step in the development and/or progression of cholesteatoma.
CYLD Binding (loss) of associated with cholesteatoma
2) Confidence 0.33 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2858283 Disease Relevance 1.05 Pain Relevance 0.06
To find the association between CYLD and NF-?
CYLD Binding (association) of
3) Confidence 0.33 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2858283 Disease Relevance 1.09 Pain Relevance 0
Excessive work stress or dissatisfaction, poor interpersonal relationships and poor communication are often seen to be associated with SBS.

6.

SBS Binding (associated) of associated with stress and sick building syndrome
4) Confidence 0.32 Published 2008 Journal Indian Journal of Occupational and Environmental Medicine Section Body Doc Link PMC2796751 Disease Relevance 0.55 Pain Relevance 0
The tumor suppressor gene CYLD, which was recently identified as the cylindromatosis gene, has a deubiquitinating enzyme (DUB) activity and inhibits activation of the transcription factor NF-?
CYLD Binding (inhibits) of associated with cancer and skin cancer
5) Confidence 0.29 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2858283 Disease Relevance 1.42 Pain Relevance 0.14
Complications of SBS
SBS Binding (Complications) of associated with short bowel syndrome
6) Confidence 0.14 Published 2005 Journal BMC Nurs Section Body Doc Link PMC549542 Disease Relevance 1.04 Pain Relevance 0.07
On the basis of a WHO report,(367) Mølhave(368) has suggested a definition for SBS.
SBS Binding (definition) of associated with sick building syndrome
7) Confidence 0.08 Published 2010 Journal Chemical Reviews Section Body Doc Link PMC2855181 Disease Relevance 1.43 Pain Relevance 0.09

General Comments

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