INT181215

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Context Info
Confidence 0.12
First Reported 2005
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.61
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (MAGEA1) nucleus (MAGEA1) cytoplasm (MAGEA1)
Anatomy Link Frequency
T cell 1
MAGEA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 2 56.16 Quite High
headache 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
anticonvulsant 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 85 98.40 Very High Very High Very High
Testicular Cancer 2 95.16 Very High Very High Very High
Cytomegalovirus Infection 4 91.16 High High
Erythema 6 86.32 High High
Hypersensitivity 6 69.24 Quite High
Pain 2 56.16 Quite High
Pressure And Volume Under Development 2 55.80 Quite High
Syndrome 9 54.40 Quite High
Contusions 1 52.16 Quite High
Death 3 48.40 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Surprisingly, 5-aza-2'-deoxycytidine demethylation treatment led to induction of MAGE-, GAGE-, PAGE-, and XAGE-type genes in tumor cells but not in normal cells [44].
Positive_regulation (induction) of MAGE associated with cancer
1) Confidence 0.12 Published 2006 Journal J Transl Med Section Body Doc Link PMC1413557 Disease Relevance 0.52 Pain Relevance 0
One patient (DU49) exhibited detectable increases in T cell precursor frequency to MAGE-A10(254–262) following in-vitro stimulation (an increase of 12 MAGE-A10-specific cells/20,000 responders).
Positive_regulation (increase) of MAGE in T cell
2) Confidence 0.01 Published 2005 Journal J Transl Med Section Body Doc Link PMC551593 Disease Relevance 1.09 Pain Relevance 0.06

General Comments

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