INT181242

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Context Info
Confidence 0.24
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (ZBTB32) nuclear chromosome (ZBTB32) nucleus (ZBTB32)
intracellular (ZBTB32) DNA binding (ZBTB32)
ZBTB32 (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 4 100.00 Very High Very High Very High
agonist 48 99.44 Very High Very High Very High
opioid receptor 10 85.88 High High
addiction 6 84.56 Quite High
tolerance 6 84.00 Quite High
Kappa opioid receptor 48 5.00 Very Low Very Low Very Low
mu opioid receptor 34 5.00 Very Low Very Low Very Low
antagonist 18 5.00 Very Low Very Low Very Low
Dynorphin 10 5.00 Very Low Very Low Very Low
Opioid 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coronary Heart Disease 4 19.04 Low Low
Myocardial Infarction 2 16.44 Low Low
Targeted Disruption 4 6.72 Low Low
Cytomegalovirus Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Specifically, agonist-induced internalization is reduced in Rog-A and enhanced in Rog-?
Negative_regulation (reduced) of Rog associated with agonist
1) Confidence 0.24 Published 2005 Journal BMC Biol Section Body Doc Link PMC551613 Disease Relevance 0 Pain Relevance 0.31
Rog-A shows no desensitization after a brief spiradoline pretreatment, while the same treatment reduces the potency of spiradoline at Rog-?
Negative_regulation (reduces) of Rog associated with potency
2) Confidence 0.24 Published 2005 Journal BMC Biol Section Body Doc Link PMC551613 Disease Relevance 0 Pain Relevance 0.30

General Comments

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