INT181323

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Context Info
Confidence 0.35
First Reported 2005
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.92
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (TNFAIP1) nucleolus (TNFAIP1) nucleus (TNFAIP1)
embryo development (TNFAIP1) cytoplasm (TNFAIP1)
Anatomy Link Frequency
B12 4
TNFAIP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
anticonvulsant 1 99.58 Very High Very High Very High
antiepileptic Drug 1 60.76 Quite High
Glutamate 1 50.24 Quite High
imagery 6 40.04 Quite Low
peripheral neuropathy 1 10.52 Low Low
Paresthesia 4 6.48 Low Low
Pain 4 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
Action potential 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Megaloblastic Anemia 2 87.56 High High
Mycobacterial Infection 20 85.96 High High
Fever 12 79.24 Quite High
Disease 3 71.00 Quite High
Obesity 1 67.28 Quite High
Weight Loss 2 66.44 Quite High
Celiac Disease 1 60.64 Quite High
Atrophic Gastritis 1 59.36 Quite High
Convulsion 7 57.00 Quite High
Neuropathy 2 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Some patients felt that the B12 injections they had been receiving in the past were effective: "I find it gives me more energy."
Regulation (effective) of B12 in B12
1) Confidence 0.35 Published 2005 Journal BMC Fam Pract Section Body Doc Link PMC554115 Disease Relevance 0 Pain Relevance 0
A second limitation was that we did not assess the knowledge and attitudes of our patients' physicians and nurses, as they may have influenced patient's expectations and perceptions regarding the effective of oral B12 therapy.
Regulation (effective) of B12 in B12
2) Confidence 0.35 Published 2005 Journal BMC Fam Pract Section Body Doc Link PMC554115 Disease Relevance 0 Pain Relevance 0
The recruitment cover letter included one sentence describing the equivalency of oral B12 therapy to injections: "Studies have shown that vitamin B12 pills are just as effective and safe as B12 injections."
Regulation (effective) of B12 in B12
3) Confidence 0.35 Published 2005 Journal BMC Fam Pract Section Body Doc Link PMC554115 Disease Relevance 0 Pain Relevance 0
It has also been reported that long term anticonvulsant therapy may have no effect on levels of vitamin B12 [11].
Neg (no) Regulation (effect) of B12 in B12 associated with anticonvulsant
4) Confidence 0.10 Published 2008 Journal J Med Case Reports Section Body Doc Link PMC2329654 Disease Relevance 0.92 Pain Relevance 0.11

General Comments

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