INT181394

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Context Info
Confidence 0.25
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.01
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
T cells 1
Il12rb1 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 97 99.40 Very High Very High Very High
cytokine 30 70.80 Quite High
agonist 44 69.36 Quite High
Inflammation 82 51.12 Quite High
chemokine 82 50.00 Quite Low
Multiple sclerosis 84 47.12 Quite Low
Demyelination 17 30.76 Quite Low
Spinal cord 14 15.36 Low Low
antagonist 11 5.00 Very Low Very Low Very Low
Neuritis 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Central Nervous System Disease 53 99.40 Very High Very High Very High
Targeted Disruption 16 96.92 Very High Very High Very High
Multiple Sclerosis 115 86.80 High High
Sprains And Strains 8 73.68 Quite High
Immunization 5 72.24 Quite High
Disease 78 63.44 Quite High
INFLAMMATION 88 51.12 Quite High
Demyelinating Disease 108 47.12 Quite Low
Hepatitis 1 27.08 Quite Low
Autoimmune Disease 7 17.48 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expression of the IL-12 p40 subunit is controlled
Gene_expression (expression) of IL-12 p40 subunit
1) Confidence 0.25 Published 2008 Journal PPAR Research Section Body Doc Link PMC2490815 Disease Relevance 0.22 Pain Relevance 0.33
Increased CCL2 expression in the CNS also resulted in a decreased IL-12 receptor expression by PLP-specific T cells.
Gene_expression (expression) of IL-12 receptor in T cells associated with central nervous system
2) Confidence 0.07 Published 2005 Journal J Neuroinflammation Section Body Doc Link PMC554759 Disease Relevance 1.79 Pain Relevance 0.31

General Comments

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