INT181410

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Context Info
Confidence 0.33
First Reported 2005
Last Reported 2008
Negated 2
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 3.52
Pain Relevance 1.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ccl3) extracellular space (Ccl3) extracellular region (Ccl3)
intracellular (Ccl3) cytoskeleton organization (Ccl3) kinase activity (Ccl3)
Ccl3 (Mus musculus)
Pain Link Frequency Relevance Heat
corticosteroid 2 97.88 Very High Very High Very High
Multiple sclerosis 74 93.56 High High
chemokine 98 88.80 High High
Central nervous system 69 84.60 Quite High
Inflammation 71 84.44 Quite High
cytokine 15 73.04 Quite High
Neuritis 6 72.72 Quite High
b2 receptor 17 50.00 Quite Low
Inflammatory response 4 29.16 Quite Low
Spinal cord 19 26.40 Quite Low
Disease Link Frequency Relevance Heat
Recurrence 17 99.24 Very High Very High Very High
Multiple Sclerosis 165 98.92 Very High Very High Very High
Disease 34 95.80 Very High Very High Very High
Demyelinating Disease 79 93.56 High High
Neurological Disease 12 90.28 High High
Central Nervous System Disease 48 84.60 Quite High
INFLAMMATION 75 84.44 Quite High
Neuromyelitis Optica 1 77.60 Quite High
Syndrome 5 75.52 Quite High
Optic Neuritis 6 73.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There was no difference in cerebral CCL3 expression in WT mice before or after EAE induction (Figure 4C).
Neg (no) Regulation (difference) of Gene_expression (expression) of CCL3 associated with multiple sclerosis
1) Confidence 0.33 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2596102 Disease Relevance 1.18 Pain Relevance 0.30
With the exception of well defined changes in the CCL2, CCL3 and CCL5 levels in the CSF during relapses, most investigators observed no differences in various clinical forms of the disease [56,61,64,66].
Neg (exception) Regulation (changes) of Gene_expression (levels) of CCL3 associated with disease and recurrence
2) Confidence 0.27 Published 2005 Journal J Neuroinflammation Section Body Doc Link PMC554759 Disease Relevance 2.34 Pain Relevance 0.76

General Comments

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