INT181416

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Context Info
Confidence 0.26
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.34
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ccl4) extracellular region (Ccl4)
Ccl4 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 134 95.68 Very High Very High Very High
fibrosis 32 79.20 Quite High
Spinal cord 8 69.32 Quite High
Central nervous system 50 52.84 Quite High
Inflammation 70 50.00 Quite Low
Demyelination 12 19.40 Low Low
Multiple sclerosis 60 5.00 Very Low Very Low Very Low
cytokine 15 5.00 Very Low Very Low Very Low
antagonist 11 5.00 Very Low Very Low Very Low
Arthritis 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 30 98.84 Very High Very High Very High
Multiple Sclerosis 79 94.84 High High
Recurrence 16 88.72 High High
Cirrhosis 52 86.24 High High
INFLAMMATION 75 84.60 Quite High
Death 13 83.04 Quite High
Injury 14 68.00 Quite High
Fibrosis 24 65.68 Quite High
Apoptosis 5 57.52 Quite High
Central Nervous System Disease 48 52.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In agreement with this, we have found that administration of fucoidan reduces CCl4-induced lipid peroxidation (data not shown).
Negative_regulation (reduces) of CCl4
1) Confidence 0.26 Published 2008 Journal Eur J Pharmacol Section Body Doc Link PMC2258315 Disease Relevance 1.00 Pain Relevance 0.10
We chose the L1.2/CCR5 transfectants for these analyses because we were able to test inhibition of CCL3, CCL3L1, the high-affinity variant for this receptor, and CCL4 in the same assay system.
Negative_regulation (inhibition) of CCL4
2) Confidence 0.22 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2526197 Disease Relevance 0.08 Pain Relevance 0.12
(CCL4) mRNA declined in correlation with the clinical recovery.
Negative_regulation (declined) of CCL4
3) Confidence 0.21 Published 2005 Journal J Neuroinflammation Section Body Doc Link PMC554759 Disease Relevance 1.25 Pain Relevance 0.10

General Comments

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