INT181417

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Context Info
Confidence 0.45
First Reported 2005
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.80
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ccl2) extracellular region (Ccl2) cytoskeleton organization (Ccl2)
cytoplasm (Ccl2)
Anatomy Link Frequency
adipose tissue 2
Ccl2 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 83 92.20 High High
Spinal cord 8 79.28 Quite High
Inflammation 84 79.20 Quite High
Central nervous system 50 62.80 Quite High
Arthritis 3 41.20 Quite Low
cytokine 17 30.16 Quite Low
Demyelination 12 29.36 Quite Low
ischemia 1 27.36 Quite Low
agonist 4 22.56 Low Low
Multiple sclerosis 60 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 11 99.52 Very High Very High Very High
Recurrence 16 98.68 Very High Very High Very High
Multiple Sclerosis 79 94.88 High High
Disease 22 86.72 High High
INFLAMMATION 92 79.20 Quite High
Central Nervous System Disease 48 62.80 Quite High
Acute Disease 2 59.36 Quite High
Vasculitis 1 43.92 Quite Low
Arthritis 4 41.20 Quite Low
Coronary Artery Disease 1 37.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Youseff et al [16] observed an increased mRNA transcription not only for MCP-1 (CCL2), but also for MIP-1?
Positive_regulation (increased) of Transcription (transcription) of MCP-1
1) Confidence 0.45 Published 2005 Journal J Neuroinflammation Section Body Doc Link PMC554759 Disease Relevance 1.37 Pain Relevance 0.10
Conversely, Trevaskis et al. have shown an increase in macrophage infiltration and increases in and CD68 and MCP-1 mRNA expression within the adipose tissue in MC3R KO mice compared to control [33].
Positive_regulation (increases) of Transcription (expression) of MCP-1 in adipose tissue associated with obesity
2) Confidence 0.39 Published 2011 Journal Journal of Aging Research Section Body Doc Link PMC3022199 Disease Relevance 0.43 Pain Relevance 0.16

General Comments

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