INT181442

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Context Info
Confidence 0.26
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.63
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Hand2) DNA binding (Hand2) protein complex (Hand2)
cytoplasm (Ccl2) extracellular space (Ccl2) extracellular region (Ccl2)
Anatomy Link Frequency
lymphocyte 2
Ccl2 (Mus musculus)
Hand2 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 7 95.92 Very High Very High Very High
Inflammation 47 84.32 Quite High
corticosteroid 2 81.84 Quite High
Multiple sclerosis 60 77.92 Quite High
chemokine 78 58.48 Quite High
Central nervous system 50 39.72 Quite Low
Neuritis 6 23.84 Low Low
Demyelination 12 5.00 Very Low Very Low Very Low
Spinal cord 8 5.00 Very Low Very Low Very Low
antagonist 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Recurrence 16 93.60 High High
INFLAMMATION 47 84.32 Quite High
Demyelinating Disease 78 77.92 Quite High
Meningitis 3 55.24 Quite High
Multiple Sclerosis 79 52.56 Quite High
Central Nervous System Disease 48 39.72 Quite Low
Neurological Disease 12 24.16 Low Low
Optic Neuritis 6 23.84 Low Low
Syndrome 5 23.72 Low Low
Disease 19 5.96 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The first consideration suggests, that the decreased CCL2 level likely relate to a decreased TH2 lymphocyte activity, as CCL2 induces TH2 polarization.
CCL2 Positive_regulation (induces) of Localization (polarization) of TH2 in lymphocyte
1) Confidence 0.26 Published 2005 Journal J Neuroinflammation Section Body Doc Link PMC554759 Disease Relevance 0.63 Pain Relevance 0.29

General Comments

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