INT181449

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Context Info
Confidence 0.24
First Reported 2005
Last Reported 2005
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.73
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ccl7, Ccl2) extracellular region (Ccl7, Ccl2) cytoskeleton organization (Ccl7, Ccl2)
cytoplasm (Ccl2)
Anatomy Link Frequency
brain 1
Ccl7 (Mus musculus)
Ccl2 (Mus musculus)
Pain Link Frequency Relevance Heat
Multiple sclerosis 60 98.08 Very High Very High Very High
chemokine 78 77.44 Quite High
Inflammation 47 58.72 Quite High
Central nervous system 50 56.24 Quite High
Demyelination 12 5.00 Very Low Very Low Very Low
Spinal cord 8 5.00 Very Low Very Low Very Low
antagonist 8 5.00 Very Low Very Low Very Low
cytokine 7 5.00 Very Low Very Low Very Low
Neuritis 6 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Demyelinating Disease 78 98.08 Very High Very High Very High
Neurological Disease 12 83.04 Quite High
Encephalitis 2 79.04 Quite High
Alzheimer's Dementia 1 76.88 Quite High
Parkinson's Disease 1 74.96 Quite High
INFLAMMATION 47 58.72 Quite High
Apoptosis 3 57.32 Quite High
Central Nervous System Disease 48 56.24 Quite High
Multiple Sclerosis 79 5.00 Very Low Very Low Very Low
Disease 19 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This analysis of CCL mRNA molecules in various regions of MS brain complements the data from previous immunohistochemical studies, and further confirms the involvement of CCL2 and CCL7 (and possibly of CCL8) in the development of pathology.
CCL7 Spec (possibly) Regulation (involvement) of CCL2 in brain associated with multiple sclerosis
1) Confidence 0.24 Published 2005 Journal J Neuroinflammation Section Body Doc Link PMC554759 Disease Relevance 0.73 Pain Relevance 0.25

General Comments

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