INT181453

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Context Info
Confidence 0.06
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.87
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ccl2) extracellular region (Ccl2) cytoskeleton organization (Ccl2)
cytoplasm (Ccl2)
Anatomy Link Frequency
T cells 3
Ccl2 (Mus musculus)
Il12rb1 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 50 100.00 Very High Very High Very High
chemokine 78 50.00 Quite Low
Inflammation 47 50.00 Quite Low
Demyelination 12 30.96 Quite Low
Spinal cord 8 11.44 Low Low
Multiple sclerosis 60 5.00 Very Low Very Low Very Low
antagonist 8 5.00 Very Low Very Low Very Low
cytokine 7 5.00 Very Low Very Low Very Low
Neuritis 6 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Central Nervous System Disease 48 100.00 Very High Very High Very High
Targeted Disruption 10 99.16 Very High Very High Very High
Multiple Sclerosis 79 86.80 High High
Sprains And Strains 8 75.92 Quite High
Immunization 5 72.24 Quite High
INFLAMMATION 47 50.00 Quite Low
Demyelinating Disease 78 30.96 Quite Low
Hepatitis 1 29.32 Quite Low
Recurrence 16 18.76 Low Low
Disease 19 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Increased CCL2 expression in the CNS also resulted in a decreased IL-12 receptor expression by PLP-specific T cells.
Gene_expression (expression) of CCL2 in T cells Positive_regulation (resulted) of Gene_expression (expression) of IL-12 receptor in T cells associated with central nervous system
1) Confidence 0.06 Published 2005 Journal J Neuroinflammation Section Body Doc Link PMC554759 Disease Relevance 1.87 Pain Relevance 0.34

General Comments

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