INT181494

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Context Info
Confidence 0.24
First Reported 2005
Last Reported 2005
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.70
Pain Relevance 1.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (NGF) signal transduction (NGF) extracellular space (NGF)
extracellular region (NGF)
Anatomy Link Frequency
nociceptors 2
TRPV3 (Homo sapiens)
NGF (Homo sapiens)
Pain Link Frequency Relevance Heat
Nerve growth factor 25 100.00 Very High Very High Very High
nociceptor 8 98.00 Very High Very High Very High
Pain 69 93.44 High High
antagonist 2 77.88 Quite High
Thermal hyperalgesia 3 75.84 Quite High
Lasting pain 2 65.08 Quite High
qutenza 6 61.96 Quite High
Mcgill questionnaire 8 51.92 Quite High
Inflammation 7 45.04 Quite Low
Dismenorea 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 70 93.44 High High
Hyperalgesia 3 75.84 Quite High
Macromastia 5 69.00 Quite High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

2 61.20 Quite High
Hypersensitivity 4 51.88 Quite High
Inflammatory Bowel Disease 1 45.60 Quite Low
INFLAMMATION 5 26.72 Quite Low
Dysmenorrhea 3 5.00 Very Low Very Low Very Low
Infection 2 5.00 Very Low Very Low Very Low
Dermatitis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It may be speculated that increased TRPV3 and TRPV4 in observed in keratinocytes may alter keratinocyte expression of NGF and other molecules, which in turn may sensitise nociceptors.


TRPV3 Spec (may) Regulation (alter) of Gene_expression (expression) of NGF in nociceptors associated with nerve growth factor and nociceptor
1) Confidence 0.24 Published 2005 Journal BMC Womens Health Section Body Doc Link PMC554997 Disease Relevance 0.64 Pain Relevance 1.07

General Comments

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