INT181528

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Context Info
Confidence 0.43
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.06
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
B cells 2
T cells 2
Ifnar1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 14 57.72 Quite High
Inflammation 23 53.92 Quite High
Arthritis 6 29.84 Quite Low
rheumatoid arthritis 1 21.60 Low Low
cytokine 27 19.28 Low Low
Demyelination 1 15.96 Low Low
Multiple sclerosis 1 9.56 Low Low
Bile 6 5.00 Very Low Very Low Very Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Immunization 36 95.16 Very High Very High Very High
Infection 105 90.52 High High
Influenza Virus Infection 8 85.92 High High
Sprains And Strains 15 84.64 Quite High
INFLAMMATION 24 53.92 Quite High
Hypersensitivity 15 50.00 Quite Low
Targeted Disruption 14 50.00 Quite Low
Togavirus Infection 8 50.00 Quite Low
Apoptosis 5 47.56 Quite Low
Synovitis 9 47.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It was also shown that CpG stimulate T cells by inducing APCs to synthesize IFN-I, which then act directly on T cells via IFNAR[37].
Positive_regulation (inducing) of Gene_expression (synthesize) of IFN-I in T cells
1) Confidence 0.43 Published 2005 Journal Respir Res Section Body Doc Link PMC555575 Disease Relevance 0.05 Pain Relevance 0.03
Viral titers in IFNAR?
Positive_regulation (titers) of Gene_expression (titers) of IFNAR
2) Confidence 0.40 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2822618 Disease Relevance 0.43 Pain Relevance 0
Type I IFN receptor expression by B cells is required for the IgG2c TI-2 antibody response
Positive_regulation (required) of Gene_expression (expression) of IFN receptor in B cells
3) Confidence 0.38 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2901065 Disease Relevance 0.33 Pain Relevance 0.06
Furthermore, L. monocytogenes induces expression of type I interferon (IFN-??)
Positive_regulation (induces) of Gene_expression (expression) of type I interferon
4) Confidence 0.05 Published 2010 Journal International Journal of Inflammation Section Body Doc Link PMC3003996 Disease Relevance 0.25 Pain Relevance 0

General Comments

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