INT181569

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Context Info
Confidence 0.09
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.70
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Edn1, Mapk8) mitochondrion (Mapk8) cell-cell signaling (Edn1)
cytosol (Mapk8) extracellular space (Edn1) signal transduction (Mapk8)
Edn1 (Rattus norvegicus)
Mapk8 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 2 100.00 Very High Very High Very High
Bioavailability 2 29.28 Quite Low
medulla 38 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 4 100.00 Very High Very High Very High
INFLAMMATION 2 100.00 Very High Very High Very High
Apoptosis 2 90.68 High High
Diabetes Mellitus 264 86.48 High High
Dyslipidemia /

Combined Dyslipidemia

2 79.96 Quite High
Hypertension 2 79.40 Quite High
Renal Disease 16 78.20 Quite High
Infection 4 72.60 Quite High
Hyperglycemia 14 69.72 Quite High
Sepsis 4 48.72 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ERK1/2 is involved in the growth response of cell while p38-MAPK and JNK are associated with cellular response to stress [7], inflammation [8] and vasoactive mediators such as endothelin-1 (ET-1) [9].
ET-1 Binding (associated) of JNK associated with stress and inflammation
1) Confidence 0.09 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC555576 Disease Relevance 1.27 Pain Relevance 0.05
ERK1/2 is involved in the growth response of cell while p38-MAPK and JNK are associated with cellular response to stress [7], inflammation [8] and vasoactive mediators such as endothelin-1 (ET-1) [9].
endothelin-1 Binding (associated) of JNK associated with stress and inflammation
2) Confidence 0.09 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC555576 Disease Relevance 1.27 Pain Relevance 0.05

General Comments

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