INT181589

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Context Info
Confidence 0.32
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 13
Total Number 14
Disease Relevance 9.47
Pain Relevance 4.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (OPN1SW) plasma membrane (OPN1SW) signal transducer activity (OPN1SW)
OPN1SW (Homo sapiens)
Pain Link Frequency Relevance Heat
behavioral therapy 318 100.00 Very High Very High Very High
spastic colon 84 98.60 Very High Very High Very High
Pain management 10 97.88 Very High Very High Very High
Lasting pain 44 97.70 Very High Very High Very High
depression 288 97.56 Very High Very High Very High
Pain 139 97.16 Very High Very High Very High
antidepressant 75 95.80 Very High Very High Very High
tolerance 1 81.80 Quite High
rheumatoid arthritis 21 75.32 Quite High
Arthritis 45 50.00 Quite Low
Disease Link Frequency Relevance Heat
Injury 151 99.82 Very High Very High Very High
Panic Disorder 605 99.80 Very High Very High Very High
Affective Disorder 9 99.70 Very High Very High Very High
Cognitive Disorder 176 99.28 Very High Very High Very High
Post-traumatic Stress Disorder 175 99.28 Very High Very High Very High
Aggression 7 99.16 Very High Very High Very High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

87 98.60 Very High Very High Very High
Pain 187 97.70 Very High Very High Very High
Depression 360 97.56 Very High Very High Very High
Agoraphobia 280 97.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Second, CBFV values were aligned according to the CBT nadir (Figure 3) and third, the CBFV nadir was aligned to the CBT nadir (Figure 4).
CBT Binding (aligned) of
1) Confidence 0.32 Published 2005 Journal J Circadian Rhythms Section Body Doc Link PMC555580 Disease Relevance 0 Pain Relevance 0
A trial of this sort provides the opportunity to examine whether trauma-focused CBT interventions are suitable for PTSD resulting from accidental injury, as opposed to repetitive trauma such as sexual abuse or natural disasters.
CBT Binding (interventions) of associated with post-traumatic stress disorder and injury
2) Confidence 0.32 Published 2010 Journal BMC Psychiatry Section Body Doc Link PMC2998467 Disease Relevance 1.57 Pain Relevance 0
They reported that individual TF-CBT was effective in reducing indicators of PTSD in children and adolescents who had experienced a single incident trauma.
TF-CBT Binding (individual) of associated with post-traumatic stress disorder and injury
3) Confidence 0.32 Published 2010 Journal BMC Psychiatry Section Body Doc Link PMC2998467 Disease Relevance 0.91 Pain Relevance 0
Consequently, mindfulness may be combined with CBT which is used to address maladaptive thoughts and beliefs, as well as pain behavior and functioning.
CBT Binding (combined) of associated with pain and behavioral therapy
4) Confidence 0.32 Published 2008 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2249749 Disease Relevance 0.36 Pain Relevance 1.03
A recent study by Craske et al (2006) raises the possibility that remaining focused on CBT for PD may be more beneficial for both principal and comorbid diagnoses than combining CBT for PD with “straying” to CBT for co-morbid disorders.


CBT Binding (combining) of associated with panic disorder and behavioral therapy
5) Confidence 0.31 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2536545 Disease Relevance 0.60 Pain Relevance 0.55
Three novel combination strategies have recently been explored in the treatment of PD with or without agoraphobia: the sequential use of pharmacotherapy and CBT, the combination of virtual reality exposure therapy with CBT, and the use of cognitive enhancers such as d-cycloserine in combination with CBT.
CBT Binding (combination) of associated with panic disorder, cognitive disorder, behavioral therapy and agoraphobia
6) Confidence 0.31 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2536545 Disease Relevance 0.78 Pain Relevance 0.43
In contrast, for follow-up (half of the studies included a follow-up), there was no significant difference in efficacy between CBT alone and a combination approach associating CBT and pharmacotherapy.
CBT Binding (associating) of associated with behavioral therapy
7) Confidence 0.31 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2536545 Disease Relevance 0.30 Pain Relevance 0.25
Another ongoing randomized controlled investigation involving the Collège de France and 3 university hospitals (in Luxembourg, Lyon, and Paris) compares the efficacy of traditional CBT, VRET, and a waiting list in patients meeting DSM-IV criteria for PD with agoraphobia (Pull et al 2006).
CBT Binding (efficacy) of associated with panic disorder, behavioral therapy and agoraphobia
8) Confidence 0.31 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2536545 Disease Relevance 1.21 Pain Relevance 0.18
This suggests CBT must be specifically applied to targeted symptoms and behaviors in order to have a measurable effect.


CBT Binding (applied) of associated with behavioral therapy
9) Confidence 0.31 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1794518 Disease Relevance 0.55 Pain Relevance 0.61
Also, the 60% remission rate in our study, which included a combination of CBT and medication, was even better than clinical studies showing 30-40% of remission rate after 8 weeks of antidepressant medication.13
CBT Binding (combination) of associated with antidepressant
10) Confidence 0.31 Published 2009 Journal Psychiatry Investigation Section Body Doc Link PMC2808793 Disease Relevance 0.37 Pain Relevance 0.20
Biomedical treatment only partly alleviates these consequences of chronic pain.14 As a result, there has been considerable interest in psychological treatment models, which address the complex interaction of biological symptoms and psychosocial factors.14 Major aims of CBT, within the broad framework of learning theory, are to improve quality of life, coping skills and physical functioning.
CBT Binding (interaction) of associated with lasting pain
11) Confidence 0.28 Published 2010 Journal Patient Prefer Adherence Section Body Doc Link PMC2915551 Disease Relevance 0.52 Pain Relevance 0.36
The CBT site was associated with the report of help seeking for CBT, massage and exercise.


CBT Binding (associated) of
12) Confidence 0.26 Published 2006 Journal BMC Psychiatry Section Abstract Doc Link PMC1501008 Disease Relevance 0.48 Pain Relevance 0.20
= 0.6 between CBT and TAU and of ?
CBT Binding (0.6) of
13) Confidence 0.23 Published 2010 Journal BMC Geriatr Section Body Doc Link PMC2877665 Disease Relevance 0.60 Pain Relevance 0.08
1) For individuals with affective disorders how does MBCT compare with group or individual CBT in terms of efficacy, acceptability and cost-effectiveness?
CBT Binding (compare) of associated with affective disorder
14) Confidence 0.12 Published 2006 Journal BMC Psychiatry Section Body Doc Link PMC1456957 Disease Relevance 0.75 Pain Relevance 0.19

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