INT181601

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Context Info
Confidence 0.30
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.90
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (TP53, WT1) nucleus (TP53, WT1) cytoplasm (TP53, WT1)
nucleolus (TP53, WT1) cell differentiation (TP53) mitochondrion (TP53)
TP53 (Homo sapiens)
WT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 2 55.12 Quite High
fibrosis 2 22.44 Low Low
abdominal pain 4 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
backache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 96 100.00 Very High Very High Very High
Repression 2 100.00 Very High Very High Very High
Fibrosis 2 22.44 Low Low
Malignant Neoplastic Disease 8 10.08 Low Low
Primitive Neuroectodermal Tumors 6 5.00 Very Low Very Low Very Low
Bone Cancer 6 5.00 Very Low Very Low Very Low
Mesothelioma 6 5.00 Very Low Very Low Very Low
Metastasis 4 5.00 Very Low Very Low Very Low
Pleural Effusion 4 5.00 Very Low Very Low Very Low
Abdominal Pain 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
WT1 is a tumor-suppressor gene that encodes a protein, which mediates transcriptional repression and interacts with p53 protein [18], product of another tumor suppressor gene, TP53, frequently deleted or mutated in many human tumors.
TP53 Binding (interacts) of WT1 associated with cancer and repression
1) Confidence 0.30 Published 2005 Journal Cytojournal Section Body Doc Link PMC555739 Disease Relevance 0.46 Pain Relevance 0.03
WT1 is a tumor-suppressor gene that encodes a protein, which mediates transcriptional repression and interacts with p53 protein [18], product of another tumor suppressor gene, TP53, frequently deleted or mutated in many human tumors.
p53 protein Binding (interacts) of WT1 associated with cancer and repression
2) Confidence 0.30 Published 2005 Journal Cytojournal Section Body Doc Link PMC555739 Disease Relevance 0.45 Pain Relevance 0.03

General Comments

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