INT181814

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Context Info
Confidence 0.06
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.37
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Gsk3b, Gata4) cell differentiation (Gsk3b) DNA binding (Gata4)
carbohydrate metabolic process (Gsk3b) protein complex (Gsk3b) cell-cell signaling (Gata4)
Anatomy Link Frequency
cardiac myocyte 1
Gsk3b (Mus musculus)
Gata4 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 1 90.32 High High
Action potential 7 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Thoracotomy 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Calcium channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertrophy 1 98.88 Very High Very High Very High
Myocardial Infarction 15 61.12 Quite High
Infarction 4 58.48 Quite High
Dilated Cardiomyopathy 1 50.40 Quite High
Targeted Disruption 1 43.84 Quite Low
Injury 2 5.00 Very Low Very Low Very Low
Body Weight 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Obesity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The importance of beta-adrenergic stimulation to the processes of differentiation and cardiac myocyte hypertrophy makes these cells particularly useful to study the Akt–GSK3 beta regulation of nuclear-expressed

GATA-4 [25] as well as its beta-adrenergic–mediated interaction with the calcineurin pathway [24].


GSK3 beta Regulation (regulation) of GATA-4 in cardiac myocyte associated with hypertrophy
1) Confidence 0.06 Published 2005 Journal PLoS Biology Section Body Doc Link PMC1064849 Disease Relevance 0.37 Pain Relevance 0.05

General Comments

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