INT181826

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Context Info
Confidence 0.35
First Reported 2005
Last Reported 2011
Negated 0
Speculated 3
Reported most in Body
Documents 4
Total Number 6
Disease Relevance 4.43
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Baat) peroxisome (Baat) transferase activity, transferring acyl groups (Baat)
lipid metabolic process (Baat) cytoplasm (Baat)
Anatomy Link Frequency
liver 2
fat 1
Baat (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 34 93.60 High High
agonist 12 87.92 High High
Glutamate 4 34.92 Quite Low
anesthesia 6 25.52 Quite Low
Eae 11 5.00 Very Low Very Low Very Low
cerebral cortex 7 5.00 Very Low Very Low Very Low
Central nervous system 5 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
medulla 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 378 100.00 Very High Very High Very High
Impaired Glucose Tolerance 25 94.24 High High
Body Weight 78 90.16 High High
Targeted Disruption 45 90.08 High High
Diabetes Mellitus 18 74.88 Quite High
Hyperlipidemia 4 74.32 Quite High
Disease 3 58.40 Quite High
Gallstones 2 58.08 Quite High
Liver Disease 2 55.36 Quite High
Weight Gain 6 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The mRNA of PEPCK, G-6-Pase and UCP-2 in liver, and mRNA of UCP-1 in BAT were analyzed by real time PCR and normalized to a housekeeping gene (36B4) (Light Cycler 480 SYBR Green, Roche Diagnostics, Indianapolis, IN).


Spec (analyzed) Transcription (analyzed) of BAT in liver
1) Confidence 0.35 Published 2011 Journal BMC Physiol Section Body Doc Link PMC3024223 Disease Relevance 0.07 Pain Relevance 0.04
The mRNA of PEPCK, G-6-Pase and UCP-2 in liver, and mRNA of UCP-1 in BAT were analyzed by real time PCR and normalized to a housekeeping gene (36B4) (Light Cycler 480 SYBR Green, Roche Diagnostics, Indianapolis, IN).


Spec (analyzed) Transcription (mRNA) of BAT in liver
2) Confidence 0.35 Published 2011 Journal BMC Physiol Section Body Doc Link PMC3024223 Disease Relevance 0.07 Pain Relevance 0.04
The mRNA and protein expression levels of molecules involved in the regulation of thermogenesis and mitochondrial function were analyzed in BAT of the experimental animals.
Spec (analyzed) Transcription (analyzed) of BAT associated with obesity
3) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2881035 Disease Relevance 1.57 Pain Relevance 0
Thus the second aim of the present study was to investigate the effect of BOF and DAI on the mRNA expression of UCP1 and UCP2 in the BAT and WAT in high-fat diet-fed mice.


Transcription (expression) of BAT in fat associated with obesity
4) Confidence 0.29 Published 2008 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2266052 Disease Relevance 1.41 Pain Relevance 0.07
There were no significant differences in UCP2 mRNA expression in BAT or WAT among the four groups (Fig. 4).


Transcription (expression) of BAT associated with obesity
5) Confidence 0.29 Published 2008 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2266052 Disease Relevance 1.01 Pain Relevance 0.05
activates the transcription of mitochondrial uncoupling protein-1 (UCP-1) in BAT through interactions with the nuclear hormone receptors PPAR?
Transcription (transcription) of BAT associated with obesity
6) Confidence 0.25 Published 2005 Journal PLoS Biology Section Body Doc Link PMC1064854 Disease Relevance 0.31 Pain Relevance 0

General Comments

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