INT181849

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Context Info
Confidence 0.86
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 4.25
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
T cells 1
IFN1@ (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 45 99.66 Very High Very High Very High
Arthritis 69 99.32 Very High Very High Very High
chemokine 12 89.12 High High
Inflammation 28 85.92 High High
rheumatoid arthritis 21 42.88 Quite Low
methotrexate 11 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
dexamethasone 3 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 77 99.32 Very High Very High Very High
Targeted Disruption 25 98.50 Very High Very High Very High
Colitis 37 97.04 Very High Very High Very High
Schistosomiasis 25 96.72 Very High Very High Very High
Disease 45 96.56 Very High Very High Very High
Immunization 24 95.40 Very High Very High Very High
Chronic Fatigue Syndrome 78 95.24 Very High Very High Very High
Chlamydia Infection 88 94.32 High High
Sprains And Strains 20 92.88 High High
INFLAMMATION 29 85.92 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Second, when FACS analysis of IFN-?
Protein_catabolism (analysis) of IFN
1) Confidence 0.86 Published 2004 Journal Arthritis Res Ther Section Body Doc Link PMC1064864 Disease Relevance 0.62 Pain Relevance 0.08
Assessment of proliferation and IFN-?
Protein_catabolism (proliferation) of IFN
2) Confidence 0.86 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2212575 Disease Relevance 1.36 Pain Relevance 0.33
knockout mice exposed to the radiation-attenuated vaccine confirming the essential role of IFN-?
Protein_catabolism (role) of IFN associated with targeted disruption
3) Confidence 0.86 Published 2008 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2553283 Disease Relevance 0.75 Pain Relevance 0.07
When the CD4+ T cells isolated from mesenteric lymph nodes of CIITA-Tg or wild type mice undergoing oxazolone-induced colitis were stimulated with anti-CD3 antibody in ex vivo, CD4+ T cells isolated from CIITA Tg mice produced larger amount of Th2 cytokine, IL-4 but lower level of IFN-?
Protein_catabolism (level) of IFN in T cells associated with colitis and cytokine
4) Confidence 0.86 Published 2006 Journal Journal of Korean Medical Science Section Body Doc Link PMC2721999 Disease Relevance 0.67 Pain Relevance 0.17
Certain cytokines increase cytotoxic ability (IL-2) and IFN-?
Protein_catabolism (ability) of IFN associated with cytokine
5) Confidence 0.86 Published 2010 Journal J Transl Med Section Body Doc Link PMC2829521 Disease Relevance 0.85 Pain Relevance 0.26

General Comments

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