INT181867

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Context Info
Confidence 0.49
First Reported 2004
Last Reported 2004
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.93
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

hydrolase activity, acting on glycosyl bonds (Neu1) plasma membrane (Neu1) lysosome (Neu1)
Neu1 (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 96 100.00 Very High Very High Very High
Infliximab 81 100.00 Very High Very High Very High
methotrexate 9 97.96 Very High Very High Very High
spinal inflammation 55 80.32 Quite High
Crohn's disease 4 79.76 Quite High
cytokine 4 57.28 Quite High
Etanercept 1 57.16 Quite High
Inflammation 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Adalimumab 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 96 100.00 Very High Very High Very High
Low Back Pain 55 80.32 Quite High
Disease 8 79.12 Quite High
Thrombocytopenia 3 73.12 Quite High
Thrombosis 2 72.32 Quite High
Infection 6 71.84 Quite High
Hepatitis 2 44.40 Quite Low
Viral Infection 1 43.44 Quite Low
Systemic Lupus Erythematosus 14 37.00 Quite Low
Autoimmune Disease 6 30.32 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The induction of ANA and aPL autoantibodies was clearly due to infliximab, especially in the RA group, because no such induction was observed in the control RA group treated with methotrexate alone.
Neg (no) Positive_regulation (induction) of Positive_regulation (induction) of aPL associated with infliximab, rheumatoid arthritis and methotrexate
1) Confidence 0.49 Published 2004 Journal Arthritis Res Ther Section Body Doc Link PMC1064868 Disease Relevance 0.93 Pain Relevance 0.72

General Comments

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