INT181899

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Context Info
Confidence 0.03
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.22
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNF, ANGPT1) extracellular space (TNF, ANGPT1) extracellular region (TNF, ANGPT1)
plasma membrane (TNF, ANGPT1) cell differentiation (ANGPT1) intracellular (TNF)
TNF (Homo sapiens)
ANGPT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 68 100.00 Very High Very High Very High
Inflammation 22 91.84 High High
cytokine 8 85.12 High High
Arthritis 15 5.00 Very Low Very Low Very Low
Osteoarthritis 3 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
analgesia 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 68 100.00 Very High Very High Very High
Hypoxia 58 100.00 Very High Very High Very High
Synovitis 17 100.00 Very High Very High Very High
INFLAMMATION 17 91.84 High High
Hyperplasia 3 37.28 Quite Low
Cancer 21 5.00 Very Low Very Low Very Low
Stress 19 5.00 Very Low Very Low Very Low
Arthritis 13 5.00 Very Low Very Low Very Low
Apoptosis 5 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similarly, the angiopoietins Ang1 and Ang2, and their cellular receptor Tie2, which are all widely expressed in RA synovitis, are regulated by both hypoxia and TNF-?
TNF Regulation (regulated) of Ang1 associated with hypoxia, synovitis and rheumatoid arthritis
1) Confidence 0.03 Published 2004 Journal Arthritis Res Ther Section Body Doc Link PMC1064874 Disease Relevance 1.22 Pain Relevance 0.33

General Comments

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