INT18192

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Context Info
Confidence 0.44
First Reported 1985
Last Reported 2010
Negated 9
Speculated 1
Reported most in Body
Documents 16
Total Number 17
Disease Relevance 9.38
Pain Relevance 3.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Alb) extracellular space (Alb) extracellular region (Alb)
enzyme binding (Alb) DNA binding (Alb) protein complex (Alb)
Anatomy Link Frequency
plasma 6
blood 4
hepatocyte 4
liver 2
bone marrow 2
Alb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
amygdala 58 100.00 Very High Very High Very High
Glutamate 8 99.84 Very High Very High Very High
anesthesia 9 99.32 Very High Very High Very High
Paracetamol 18 99.26 Very High Very High Very High
Etanercept 2 98.12 Very High Very High Very High
spinal inflammation 1 95.52 Very High Very High Very High
long-term potentiation 3 94.88 High High
methotrexate 2 93.56 High High
Infliximab 4 91.64 High High
cINOD 7 91.32 High High
Disease Link Frequency Relevance Heat
Stress 139 99.82 Very High Very High Very High
Non-small-cell Lung Cancer 88 99.36 Very High Very High Very High
Toxicity 117 98.90 Very High Very High Very High
Hemorrhage 5 97.80 Very High Very High Very High
Depression 75 96.68 Very High Very High Very High
Pneumonia 72 95.72 Very High Very High Very High
Low Back Pain 1 95.52 Very High Very High Very High
Appetite Loss 102 94.76 High High
Hypoalbuminemia 85 94.08 High High
Lower Respiratory Tract Infection 2 92.28 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Circulating levels of glucose, lactate, citrate and albumin were not modified by glutamate.
Neg (not) Regulation (modified) of Gene_expression (levels) of albumin associated with glutamate
1) Confidence 0.44 Published 1990 Journal Am. J. Cardiol. Section Abstract Doc Link 1967510 Disease Relevance 0.30 Pain Relevance 0.48
[Relationship between changes in estimated and measured blood concentrations of propofol and serum albumin concentration during propofol anesthesia: effects of intraoperative bleeding (a case report)].
Regulation (measured) of Gene_expression (concentration) of albumin in blood associated with anesthesia and hemorrhage
2) Confidence 0.42 Published 2000 Journal Masui Section Title Doc Link 10846389 Disease Relevance 0.26 Pain Relevance 0.30
Pretreatment with DES resulted in significant increases in cumulative synthesis of factors II (65%) and VII (76%) and significant reduction in cumulative synthesis of both antithrombin III (20%; P = .03) and plasminogen (27%; P less than .01) compared to control perfusions, but synthesis of fibrinogen, fibronectin, and albumin was not significantly affected by addition of the hormone.
Neg (not) Regulation (affected) of Gene_expression (synthesis) of albumin
3) Confidence 0.40 Published 1985 Journal Blood Section Abstract Doc Link 4016277 Disease Relevance 0 Pain Relevance 0.08
Several processes control plasma albumin concentration, including absolute rate of albumin synthesis and fractional catabolic rate (FCR), among others.
Regulation (rate) of Gene_expression (concentration) of albumin in plasma
4) Confidence 0.36 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2843671 Disease Relevance 0.88 Pain Relevance 0.03
Several processes control plasma albumin concentration, including absolute rate of albumin synthesis and fractional catabolic rate (FCR), among others.
Regulation (control) of Gene_expression (concentration) of albumin in plasma
5) Confidence 0.36 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2843671 Disease Relevance 0.88 Pain Relevance 0
Therefore, we thought it would be useful not only for determining nutritional status, but also for predicting toxicity in patients with NSCLC under chemotherapy, given that albumin levels are not influenced solely by the oncologic process, but also by the patients protein and caloric intake prior to and during treatment.
Neg (not) Regulation (influenced) of Gene_expression (levels) of albumin associated with toxicity and non-small-cell lung cancer
6) Confidence 0.36 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2843671 Disease Relevance 1.47 Pain Relevance 0
Several processes control plasma albumin concentration, including absolute rate of albumin synthesis and fractional catabolic rate (FCR), among others.
Regulation (rate) of Gene_expression (synthesis) of albumin in plasma
7) Confidence 0.36 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2843671 Disease Relevance 0.93 Pain Relevance 0.03
The combined effects of orchiectomy and estrogen administration on synthesis of selected hepatic secretory proteins--antithrombin (AT) III, plasminogen, fibrinogen, factor II (prothrombin), factor VII, fibronectin, and albumin--were studied using the isolated rat liver perfused in vitro for ten hours.
Regulation (effects) of Gene_expression (synthesis) of albumin in liver
8) Confidence 0.29 Published 1985 Journal Blood Section Abstract Doc Link 4016277 Disease Relevance 0 Pain Relevance 0.09
Patients and controls did not differ in the levels of serum albumin, creatinine, aspartate aminotransferase, and alanine aminotransferase.
Neg (not) Regulation (differ) of Gene_expression (levels) of serum albumin
9) Confidence 0.29 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1297572 Disease Relevance 0.46 Pain Relevance 0.25
METHODS: We investigated the effect of incubation of rat hepatocytes and 3 hepatocyte cell lines with acetaminophen or N-acetyl-p-benzoquinoneimine on LDH release, glutathione status, mitochondrial function, CYP1A activity, albumin synthesis and DNA content.
Spec (investigated) Regulation (effect) of Gene_expression (synthesis) of albumin in hepatocyte
10) Confidence 0.21 Published 1999 Journal J. Hepatol. Section Body Doc Link 10580581 Disease Relevance 0.10 Pain Relevance 0
Predator stress induced changes in ALB and amygdala neural transmission are
Regulation (changes) of in amygdala Gene_expression (transmission) of ALB in neural associated with stress and amygdala
11) Confidence 0.19 Published 2009 Journal Neural Plasticity Section Body Doc Link PMC2664642 Disease Relevance 1.36 Pain Relevance 0.92
After exposure to acetaminophen, significant cell damage of gel entrapped hepatocytes was detected at 48 h while hepatocyte monolayer was not so sensitive except for albumin synthesis and this difference between two hepatocyte systems was similar on hepatotoxic response to antituberculosis drugs including rifampicin and isoniazid.
Neg (except) Regulation (sensitive) of Neg (except) Gene_expression (synthesis) of albumin in hepatocyte associated with paracetamol
12) Confidence 0.12 Published 2006 Journal Toxicol. Lett. Section Abstract Doc Link 16814964 Disease Relevance 0.47 Pain Relevance 0.16
Our data are compatible with classical findings that gender influences red blood
                   cell (RBC) measurements and albumin levels. 
Regulation (influences) of Gene_expression (levels) of albumin in blood
13) Confidence 0.08 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2391294 Disease Relevance 0.26 Pain Relevance 0
In contrast, these concentrations of acetaminophen (< or = 1 mM) did not significantly alter the production of secreted albumin, determined immunologically, or cause detectable toxicity.
Neg (not) Regulation (alter) of Gene_expression (production) of albumin associated with toxicity and paracetamol
14) Confidence 0.03 Published 1999 Journal Toxicol. Sci. Section Abstract Doc Link 10330681 Disease Relevance 0.10 Pain Relevance 0.84
However, PPI users and non-users had no difference in average serum albumin levels among hospitalized older patients as demonstrated in our previous study [30].
Neg (no) Regulation (difference) of Gene_expression (levels) of albumin
15) Confidence 0.03 Published 2010 Journal BMC Geriatr Section Body Doc Link PMC2909244 Disease Relevance 1.08 Pain Relevance 0.04
Serum concentrations of albumin, AST, ALT, GGT and alkaline phosphate were followed and did not change for five months.
Neg (not) Regulation (change) of Gene_expression (concentrations) of albumin
16) Confidence 0.03 Published 2007 Journal Clin. Rheumatol. Section Abstract Doc Link 16550301 Disease Relevance 0.70 Pain Relevance 0.35
The levels of hemoglobin (Hb), white blood cell (WBC) and platelet counts (PLT), bone marrow infiltration, serum calcium (Ca), creatinine, albumin, CRP, LDH, beta2-microglobulin did not change significantly before and after RT.
Neg (not) Regulation (change) of Gene_expression (levels) of albumin in bone marrow
17) Confidence 0.03 Published 2006 Journal J BUON Section Body Doc Link 17318951 Disease Relevance 0.13 Pain Relevance 0

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