INT181965

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.07
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.83
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (Gpi1) carbohydrate metabolic process (Gpi1) cytoplasm (Gpi1)
cytosol (Gpi1) extracellular space (Gpi1) extracellular region (Gpi1)
Anatomy Link Frequency
macrophages 2
Gpi1 (Mus musculus)
Pain Link Frequency Relevance Heat
Arthritis 96 100.00 Very High Very High Very High
rheumatoid arthritis 58 94.96 High High
cytokine 3 69.52 Quite High
Inflammation 15 17.40 Low Low
cva 7 5.00 Very Low Very Low Very Low
spinal inflammation 4 5.00 Very Low Very Low Very Low
headache 4 5.00 Very Low Very Low Very Low
methotrexate 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 102 100.00 Very High Very High Very High
Immunization 16 99.88 Very High Very High Very High
Hemophagocytic Lymphohistiocytosis 22 97.08 Very High Very High Very High
Rheumatoid Arthritis 58 94.96 High High
Sprains And Strains 26 92.24 High High
Recurrence 1 91.60 High High
Infection 10 79.28 Quite High
Chronic Myeloid Leukemia 1 73.52 Quite High
Disease 29 72.36 Quite High
Thrombosis 25 71.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mutations of the PIG-A gene disrupt the first step of GPI biosynthesis leading to an absence of the GPI anchor and, in turn, a marked deficiency of all GPI linked proteins.11
Negative_regulation (absence) of Gene_expression (anchor) of GPI
1) Confidence 0.07 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2789686 Disease Relevance 0.37 Pain Relevance 0
Development of G6PI arthritis is associated with a strong antibody response to G6PI and a weak response to type II collagen
Negative_regulation (Development) of Gene_expression (arthritis) of G6PI associated with arthritis
2) Confidence 0.06 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1297579 Disease Relevance 2.03 Pain Relevance 0.38
The exact mechanisms that would link deficient NK cell function and, in some cases, depressed perforin expression with the expansion of activated macrophages are not clear.
Negative_regulation (depressed) of Gene_expression (expression) of NK in macrophages
3) Confidence 0.03 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1064882 Disease Relevance 0.44 Pain Relevance 0.13

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox