INT18197

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Context Info
Confidence 0.46
First Reported 1989
Last Reported 1990
Negated 1
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0
Pain Relevance 2.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ghrh, Ggh) extracellular region (Ghrh, Ggh) cytosol (Ggh)
lysosome (Ggh)
Ghrh (Rattus norvegicus)
Ggh (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Clonidine 18 99.40 Very High Very High Very High
antagonist 5 97.12 Very High Very High Very High
Somatostatin 11 93.60 High High
anesthesia 2 90.68 High High
agonist 1 90.56 High High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the sham-operated animals, GHRH stimulated GH secretion on day 90, but not on day 30.
GHRH Neg (not) Positive_regulation (stimulated) of Localization (secretion) of GH
1) Confidence 0.46 Published 1990 Journal Acta Endocrinol. Section Abstract Doc Link 2109443 Disease Relevance 0 Pain Relevance 0.09
Orchidectomy on day 83 reduced this GHRH-induced GH secretion on day 90.
GHRH Positive_regulation (induced) of Localization (secretion) of GH
2) Confidence 0.33 Published 1990 Journal Acta Endocrinol. Section Abstract Doc Link 2109443 Disease Relevance 0 Pain Relevance 0.08
In vitro, clonidine had no stimulatory effect on GHRH-stimulated GH secretion.
GHRH Positive_regulation (stimulated) of Localization (secretion) of GH associated with clonidine
3) Confidence 0.31 Published 1989 Journal Clin. Endocrinol. (Oxf) Section Abstract Doc Link 2514051 Disease Relevance 0 Pain Relevance 1.17
Propranolol (1-100 microM) had no significant effect on basal GH secretion or GH secretion stimulated by rat GRF.
GRF Positive_regulation (stimulated) of Localization (secretion) of GH
4) Confidence 0.25 Published 1990 Journal Endocrinology Section Abstract Doc Link 1967576 Disease Relevance 0 Pain Relevance 0.88

General Comments

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