INT181991

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Context Info
Confidence 0.01
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.70
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (ELOVL1) endoplasmic reticulum (ELOVL1)
Anatomy Link Frequency
endothelial cell 2
ELOVL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 10 96.40 Very High Very High Very High
cytokine 3 93.24 High High
fibrosis 24 89.28 High High
metalloproteinase 10 50.00 Quite Low
Arthritis 3 5.00 Very Low Very Low Very Low
Sicca syndrome 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Rheumatism 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Systemic Sclerosis 67 100.00 Very High Very High Very High
INFLAMMATION 10 96.40 Very High Very High Very High
Myocardial Infarction 1 91.32 High High
Fibrosis 23 89.28 High High
Autoimmune Disease 3 85.76 High High
Injury 2 65.36 Quite High
Pulmonary Fibrosis 4 62.16 Quite High
Hypoxia 1 61.52 Quite High
Cirrhosis 3 52.00 Quite High
Disease 10 45.08 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The overproduced MMP-9 may induce microvascular damage and leakage of substances that further augment endothelial cell damage or fibroblast activation in SSc.
Positive_regulation (augment) of Positive_regulation (activation) of SSc in endothelial cell associated with systemic sclerosis
1) Confidence 0.01 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1064883 Disease Relevance 1.70 Pain Relevance 0.51

General Comments

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