INT181995

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Context Info
Confidence 0.01
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.38
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (TIMP1, Mmp9) peptidase activity (Mmp9) extracellular space (Mmp9)
aging (TIMP1) proteinaceous extracellular matrix (Mmp9) extracellular matrix organization (Mmp9)
Anatomy Link Frequency
fibroblasts 1
TIMP1 (Homo sapiens)
Mmp9 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 10 100.00 Very High Very High Very High
Chronic pancreatitis 1 92.64 High High
fibrosis 24 89.60 High High
rheumatoid arthritis 1 79.64 Quite High
Inflammation 10 77.56 Quite High
Arthritis 3 71.12 Quite High
Rheumatism 1 50.00 Quite Low
cytokine 3 5.00 Very Low Very Low Very Low
Sicca syndrome 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Systemic Sclerosis 67 97.36 Very High Very High Very High
Pancreatitis 1 92.64 High High
Cirrhosis 3 91.60 High High
Asthma 3 90.32 High High
Pulmonary Fibrosis 4 89.60 High High
Fibrosis 23 87.96 High High
Systemic Lupus Erythematosus 1 82.60 Quite High
Uveitis 1 81.24 Quite High
Syndrome 1 80.44 Quite High
Rheumatoid Arthritis 1 79.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, we measured the expression of MMP-9 and tissue inhibitor of metalloproteinase-1 (TIMP-1), an inhibitor of MMP-9, in the sera and culture supernatants of dermal fibroblasts from SSc patients and compared them with serum concentrations of transforming growth factor ?
metalloproteinase-1 Negative_regulation (inhibitor) of MMP-9 in fibroblasts associated with metalloproteinase and systemic sclerosis
1) Confidence 0.01 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1064883 Disease Relevance 1.38 Pain Relevance 0.40

General Comments

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