INT182016

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Context Info
Confidence 0.25
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 2.46
Pain Relevance 1.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Acr) protein complex (Acr)
Anatomy Link Frequency
joints 1
Acr (Mus musculus)
Pain Link Frequency Relevance Heat
methotrexate 24 98.76 Very High Very High Very High
Infliximab 176 98.44 Very High Very High Very High
rheumatoid arthritis 128 82.32 Quite High
psoriasis 79 74.40 Quite High
Arthritis 51 70.76 Quite High
Pain 5 59.88 Quite High
Rheumatism 1 6.28 Low Low
Inflammation 27 5.00 Very Low Very Low Very Low
cytokine 9 5.00 Very Low Very Low Very Low
Etanercept 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Albuminuria 8 98.96 Very High Very High Very High
Injury 16 98.20 Very High Very High Very High
Pre-eclampsia 144 93.56 High High
Fatigue 5 91.04 High High
Hypersensitivity 10 90.88 High High
Spontaneous Abortion 5 87.80 High High
Rheumatoid Arthritis 128 82.32 Quite High
Psoriasis 84 74.40 Quite High
Pressure And Volume Under Development 39 72.44 Quite High
Seronegative Spondarthritis 11 70.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Figure 3A shows that ACR levels in CBA/J x DBA/2 mice were reduced by pravastatin.
Gene_expression (levels) of ACR
1) Confidence 0.25 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965104 Disease Relevance 0.65 Pain Relevance 0
On day 15 of pregnancy, ACR levels in CBA/J x DBA/2 mice treated with VEGF121 were not different from values in control matings (Fig 4E).
Gene_expression (levels) of ACR
2) Confidence 0.22 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965104 Disease Relevance 0.67 Pain Relevance 0
(5 ng/ml) are shown in Fig. 3, stratified by ACR response observed at week 54.
Gene_expression (response) of ACR
3) Confidence 0.16 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1064892 Disease Relevance 0.21 Pain Relevance 0.35
Levels were higher for the good responders (ACR response ?
Gene_expression (response) of ACR
4) Confidence 0.16 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1064892 Disease Relevance 0.20 Pain Relevance 0.34
At week 54, the ACR response was consistent whether or not methotrexate had been used.
Gene_expression (response) of ACR associated with methotrexate
5) Confidence 0.12 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2643098 Disease Relevance 0.45 Pain Relevance 0.99
However, the ACR70 response criteria are not an adequate measure for remission as the concordance between ACR70 and DAS remission is low and ACR70 responders have a higher number of tender or swollen joints or ESR than patients in DAS remission [25].
Gene_expression (remission) of ACR70 in joints
6) Confidence 0.01 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1779387 Disease Relevance 0.26 Pain Relevance 0.06

General Comments

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