INT18202

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Context Info
Confidence 0.80
First Reported 1980
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 2.76
Pain Relevance 2.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Adrb3) plasma membrane (Adrb3) nucleus (Adrb3)
signal transducer activity (Adrb3)
Anatomy Link Frequency
coronary artery 1
caecum 1
adrenal medulla 1
Adrb3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 11 100.00 Very High Very High Very High
anesthesia 2 100.00 Very High Very High Very High
Catecholamine 6 99.96 Very High Very High Very High
medulla 3 98.68 Very High Very High Very High
Clonidine 3 94.68 High High
noradrenaline 5 94.44 High High
antagonist 3 93.52 High High
Chronic pancreatitis 5 92.56 High High
Calcium channel 3 90.52 High High
Hippocampus 2 89.84 High High
Disease Link Frequency Relevance Heat
Stress 16 100.00 Very High Very High Very High
Hypoglycemia 4 99.60 Very High Very High Very High
Pancreatitis 5 92.56 High High
Hypotension 5 91.52 High High
Diabetes Mellitus 7 90.96 High High
Urological Neuroanatomy 2 90.48 High High
Cv General 3 Under Development 2 80.72 Quite High
Shock 2 76.96 Quite High
Pressure And Volume Under Development 1 74.40 Quite High
Hypertension 1 69.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Beta-adrenoceptor blocking agents release catecholamines from rat adrenal medulla.
Localization (release) of Beta-adrenoceptor in adrenal medulla associated with medulla, anesthesia and catecholamine
1) Confidence 0.80 Published 1980 Journal Eur. J. Pharmacol. Section Title Doc Link 6102919 Disease Relevance 0.49 Pain Relevance 0.32
Stimulation of bicarbonate secretion by alpha- and beta-adrenoceptor agonists in rat caecum in vitro.
Localization (secretion) of beta-adrenoceptor in caecum associated with agonist
2) Confidence 0.62 Published 1995 Journal Eur. J. Pharmacol. Section Title Doc Link 7737304 Disease Relevance 0 Pain Relevance 0.47
Isoproterenol, a beta-adrenoceptor agonist, significantly stimulated corticosterone secretion.
Localization (secretion) of beta-adrenoceptor associated with agonist
3) Confidence 0.34 Published 1989 Journal Neurochem. Res. Section Abstract Doc Link 2628787 Disease Relevance 0.09 Pain Relevance 0.42
Also, the beta-adrenoceptor agonist isoproterenol at a concentration of 10(-7) mol/L significantly stimulated glucagon secretion as compared with basal levels in both normal (751 +/- 130 v 347 +/- 41 ng/L, P < .05) and STZ-D rats (182 +/- 22 v 92 +/- 20 ng/L, P < .01).
Localization (secretion) of beta-adrenoceptor associated with agonist
4) Confidence 0.17 Published 1993 Journal Metab. Clin. Exp. Section Abstract Doc Link 8102194 Disease Relevance 0.16 Pain Relevance 0.26
In an additional experiment, glucose recovery did not occur after hypoglycemia during concomitant beta-adrenoceptor blockade in these patients.
Localization (blockade) of beta-adrenoceptor associated with hypoglycemia
5) Confidence 0.15 Published 1990 Journal Metab. Clin. Exp. Section Abstract Doc Link 1967815 Disease Relevance 1.02 Pain Relevance 0.42
To study the involvement of a beta-adrenoceptor mechanism in stress-induced peptide secretion, rats were treated with D-propranolol or L-propranolol 40 min before stress exposure.
Localization (secretion) of beta-adrenoceptor associated with stress
6) Confidence 0.14 Published 1984 Journal Endocrinology Section Abstract Doc Link 6086282 Disease Relevance 0.79 Pain Relevance 0.08
In a study of canine coronary arteries, localization of beta-adrenoceptor subtypes was documented, with the beta1-adrenoceptor predominantly found in the conduit coronary artery.
Localization (localization) of beta-adrenoceptor in coronary artery
7) Confidence 0.04 Published 2002 Journal Curr Med Res Opin Section Abstract Doc Link 12487507 Disease Relevance 0.21 Pain Relevance 0.46

General Comments

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