INT182051

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Context Info
Confidence 0.18
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.77
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il18) extracellular region (Il18) cytoplasm (Il18)
Anatomy Link Frequency
cartilage 1
Il18 (Mus musculus)
Il1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 12 98.88 Very High Very High Very High
Arthritis 7 89.68 High High
chemokine 1 79.80 Quite High
rheumatoid arthritis 17 50.00 Quite Low
Osteoarthritis 1 39.76 Quite Low
cytokine 12 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 6 98.88 Very High Very High Very High
Pressure And Volume Under Development 1 92.40 High High
INFLAMMATION 9 90.56 High High
Experimental Arthritis 2 67.28 Quite High
Disease 6 56.64 Quite High
Rheumatoid Arthritis 17 50.00 Quite Low
Osteoarthritis 1 39.76 Quite Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Psoriasis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
/IL-1 deficient mice, Joosten and colleagues subsequently demonstrated that whilst IL-18-induced joint inflammation is independent of IL-1, cartilage degradation requires IL-18 induced IL-1?
IL-18 Positive_regulation (induced) of IL-1 in cartilage associated with inflammation and arthritis
1) Confidence 0.18 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1064903 Disease Relevance 0.77 Pain Relevance 0.38

General Comments

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