INT182077
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
PD81,723 alone behaves as an allosteric agonist, promoting the A1 AR to its active conformation (R*) and, thus, potentiates the A1 AR constitutive receptor activity. | |||||||||||||||
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Adenosine receptors (ARs) are G protein-coupled receptors, consisting of A1, A2A, A2B and A3 subtypes, activated by the endogenous agonist adenosine and blocked by natural antagonists, such as caffeine and theophylline. | |||||||||||||||
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A single scaling exponent represents the limit as N and n approach infinity; however, applicable to real life data sets, the linear relationship between log F(n) and log n has been noted to be distinct for small n (n < 11) and large n (11 < n > 10,000), yielding two lines with two slopes, labelled the scaling exponents a1 and a2, respectively. | |||||||||||||||
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In keeping with these early results, in the INTERHEART case-control study on risk factors associated with myocardial infarction in 52 countries, an increase in apo B/apo A1 ratio was shown to be the strongest risk factor for myocardial infarction [5]. | |||||||||||||||
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General Comments
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