INT182126

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Context Info
Confidence 0.03
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.86
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IRF6) extracellular space (SELE) cell adhesion (SELE)
plasma membrane (SELE) nucleus (IRF6) DNA binding (IRF6)
Anatomy Link Frequency
endothelial cells 2
IRF6 (Homo sapiens)
SELE (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 7 100.00 Very High Very High Very High
Inflammation 7 91.96 High High
COX2 2 90.16 High High
Inflammatory response 3 83.04 Quite High
medulla 3 81.00 Quite High
vagus nerve 2 75.08 Quite High
dexamethasone 1 26.00 Quite Low
cva 1 19.96 Low Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
Locus ceruleus 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 2 100.00 Very High Very High Very High
Sepsis 45 98.92 Very High Very High Very High
Infection 7 94.52 High High
INFLAMMATION 14 91.96 High High
Cancer 2 66.40 Quite High
Necrosis 2 65.84 Quite High
Syndrome 1 21.40 Low Low
Thrombophilia 1 21.04 Low Low
Cv General 3 Under Development 1 19.96 Low Low
Cerebrovascular Disease 1 18.64 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both lipopolysaccharide (LPS) and proinflammatory cytokines induce the expression of CD40, vascular adhesion molecule-1 or intercellular adhesion molecule-1, and E-selectin on human brain microvessel endothelial cells [20-24].
LPS Positive_regulation (induce) of Gene_expression (expression) of E-selectin in endothelial cells associated with adhesions and cytokine
1) Confidence 0.03 Published 2005 Journal Crit Care Section Body Doc Link PMC1065096 Disease Relevance 0.86 Pain Relevance 0.34

General Comments

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