INT182226

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Context Info
Confidence 0.44
First Reported 2005
Last Reported 2005
Negated 0
Speculated 3
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 3.64
Pain Relevance 2.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CXCR5) signal transducer activity (CXCR5)
Anatomy Link Frequency
macrophages 4
B lymphocytes 1
T lymphocytes 1
CXCR5 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 488 100.00 Very High Very High Very High
chemokine 262 97.04 Very High Very High Very High
Inflammation 51 83.92 Quite High
Osteoarthritis 19 71.88 Quite High
cytokine 13 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Rheumatism 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 488 100.00 Very High Very High Very High
Systemic Lupus Erythematosus 39 99.72 Very High Very High Very High
INFLAMMATION 52 83.92 Quite High
Osteoarthritis 23 71.88 Quite High
Disease 27 71.12 Quite High
Autoimmune Disease 2 68.40 Quite High
Adhesions 3 5.00 Very Low Very Low Very Low
Immunodeficiency 3 5.00 Very Low Very Low Very Low
Rheumatic Diseases 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The increased numbers of B lymphocytes, T lymphocytes and macrophages producing CXCR5 in the RA synovium are probably responsible for the increased expression of the receptor in this chronically inflamed tissue.
Spec (probably) Regulation (responsible) of Gene_expression (producing) of CXCR5 in macrophages associated with rheumatoid arthritis
1) Confidence 0.44 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1065316 Disease Relevance 0.89 Pain Relevance 0.52
In patients with SLE, significant changes in CXCR5 expression were seen.
Regulation (changes) of Gene_expression (expression) of CXCR5 associated with systemic lupus erythematosus
2) Confidence 0.36 Published 2005 Journal Arthritis Res Ther Section Abstract Doc Link PMC1257429 Disease Relevance 0.96 Pain Relevance 0.57
The increased numbers of B lymphocytes, T lymphocytes and macrophages producing CXCR5 in the RA synovium are probably responsible for the increased expression of the receptor in this chronically inflamed tissue.
Spec (probably) Regulation (responsible) of in B lymphocytes Gene_expression (producing) of CXCR5 in macrophages associated with rheumatoid arthritis
3) Confidence 0.15 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1065316 Disease Relevance 0.89 Pain Relevance 0.52
The increased numbers of B lymphocytes, T lymphocytes and macrophages producing CXCR5 in the RA synovium are probably responsible for the increased expression of the receptor in this chronically inflamed tissue.
Spec (probably) Regulation (responsible) of in T lymphocytes Gene_expression (producing) of CXCR5 in macrophages associated with rheumatoid arthritis
4) Confidence 0.15 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1065316 Disease Relevance 0.89 Pain Relevance 0.52

General Comments

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