INT182227

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Context Info
Confidence 0.60
First Reported 2005
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.07
Pain Relevance 0.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CXCL13) extracellular space (CXCL13) extracellular region (CXCL13)
cell-cell signaling (CXCL13)
Anatomy Link Frequency
synovium 1
CXCL13 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 142 99.68 Very High Very High Very High
chemokine 66 94.40 High High
Inflammation 36 86.24 High High
aspirin 5 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
cocaine 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
lidocaine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 142 99.68 Very High Very High Very High
Eczema 31 99.64 Very High Very High Very High
INFLAMMATION 38 86.24 High High
Rhinitis 62 85.28 High High
Eosinophilic Esophagitis 5 72.72 Quite High
Disease 29 62.84 Quite High
Chronic Sinusitis 14 60.24 Quite High
Nasal Polyps 6 59.52 Quite High
Asthma 17 50.00 Quite Low
Hypersensitivity 7 18.92 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The microarrays showed that the mRNA for CXCL13, the only known ligand of CXCR5, was present in the RA synovium and not in the non-RA synovium.
Neg (not) Transcription (present) of CXCL13 in synovium associated with rheumatoid arthritis
1) Confidence 0.60 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1065316 Disease Relevance 0.89 Pain Relevance 0.55
Both aCRSwNP and AD showed increased transcription of CCL18 (PARC), CCL22 (MDC), and CXCL13.
Transcription (transcription) of CXCL13 associated with eczema
2) Confidence 0.31 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2897889 Disease Relevance 1.18 Pain Relevance 0.26

General Comments

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