INT182236

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Context Info
Confidence 0.58
First Reported 2005
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.07
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CCR7) intracellular (CCR7) signal transducer activity (CCR7)
Anatomy Link Frequency
CD86 1
PDL-1 1
synovium 1
CCR7 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 144 100.00 Very High Very High Very High
chemokine 74 99.68 Very High Very High Very High
Inflammation 79 50.00 Quite Low
Chronic pancreatitis 20 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Rheumatism 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 144 100.00 Very High Very High Very High
Adenocarcinoma 180 88.72 High High
INFLAMMATION 79 50.00 Quite Low
Disease 16 9.36 Low Low
Cancer 68 5.00 Very Low Very Low Very Low
Pancreatitis 20 5.00 Very Low Very Low Very Low
Pancreatic Cancer 10 5.00 Very Low Very Low Very Low
Breast Cancer 8 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 8 5.00 Very Low Very Low Very Low
Fibrosis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study mRNA for other chemokine receptors were detected in the RA synovium, such as CXCR1, CXCR2, CXCR4, Bob, CCR1, CCR2a, CCR7, CCR9 and CX3CR1 (CXCR3 was not on the microarray).
Neg (not) Transcription (detected) of CCR7 in synovium associated with chemokine and rheumatoid arthritis
1) Confidence 0.58 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1065316 Disease Relevance 0.45 Pain Relevance 0.47
The purified MDCs and PDCs were matured with the TLR3 ligand Poly I:C and TLR9 ligand CpG, respectively, and assessed for CD40, CD83, CD86, PDL-1, ICOSL, B7H3, DCIR, CCR5, and CCR7 expression levels.
Transcription (levels) of CCR7 in PDL-1
2) Confidence 0.43 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2955544 Disease Relevance 0.31 Pain Relevance 0
The purified MDCs and PDCs were matured with the TLR3 ligand Poly I:C and TLR9 ligand CpG, respectively, and assessed for CD40, CD83, CD86, PDL-1, ICOSL, B7H3, DCIR, CCR5, and CCR7 expression levels.
Transcription (levels) of CCR7 in CD86
3) Confidence 0.15 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2955544 Disease Relevance 0.31 Pain Relevance 0

General Comments

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