INT182239

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Context Info
Confidence 0.36
First Reported 2005
Last Reported 2006
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.16
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CCR7) intracellular (CCR7) signal transducer activity (CCR7)
CCR7 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 151 100.00 Very High Very High Very High
chemokine 113 96.76 Very High Very High Very High
Arthritis 50 66.88 Quite High
cytokine 5 52.12 Quite High
Inflammation 43 50.00 Quite Low
methotrexate 14 11.72 Low Low
antagonist 3 5.00 Very Low Very Low Very Low
Rheumatism 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 151 100.00 Very High Very High Very High
Immunodeficiency 1 95.12 Very High Very High Very High
Juvenile Chronic Polyarthritis 40 66.88 Quite High
INFLAMMATION 42 50.00 Quite Low
Osteoarthritis 1 14.80 Low Low
Disease 16 5.00 Very Low Very Low Very Low
Arthritis 10 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Rheumatic Diseases 2 5.00 Very Low Very Low Very Low
Coagulation Disorder 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The detection of CCR7 and CCR9 in RA was only possible after extended exposure times, but at the time points used for quantification no regulation was demonstrated.
Spec (possible) Negative_regulation (possible) of Gene_expression (detection) of CCR7 associated with rheumatoid arthritis
1) Confidence 0.36 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1065316 Disease Relevance 1.09 Pain Relevance 0.74
The memory population may be further divided by the expression or loss of expression of CCR7 [12].
Negative_regulation (loss) of Gene_expression (expression) of CCR7
2) Confidence 0.33 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526593 Disease Relevance 0.07 Pain Relevance 0.17

General Comments

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