INT182258

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Context Info
Confidence 0.15
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.47
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (EDN1, MMP1) peptidase activity (MMP1) extracellular space (EDN1)
proteinaceous extracellular matrix (MMP1) cell-cell signaling (EDN1) cytoplasm (EDN1)
EDN1 (Homo sapiens)
MMP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 35 95.28 Very High Very High Very High
Inflammation 1 88.08 High High
Pain 1 27.40 Quite Low
rheumatoid arthritis 3 23.16 Low Low
cytokine 3 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 36 95.28 Very High Very High Very High
INFLAMMATION 1 88.08 High High
Disease 1 83.76 Quite High
Pain 1 27.40 Quite Low
Rheumatoid Arthritis 3 23.16 Low Low
Apoptosis 14 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Stress 3 5.00 Very Low Very Low Very Low
Osteoporosis 1 5.00 Very Low Very Low Very Low
Rheumatic Diseases 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Among all the MMPs, we have recently demonstrated an induction in the synthesis, secretion and activation of two collagenases (MMP-1 and MMP-13) by ET-1 [2].
ET-1 Positive_regulation (induction) of Positive_regulation (activation) of MMP-1
1) Confidence 0.15 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1065327 Disease Relevance 0.47 Pain Relevance 0.19

General Comments

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