INT182269

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Context Info
Confidence 0.17
First Reported 2005
Last Reported 2005
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.31
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (EDN1, MMP1) peptidase activity (MMP1) extracellular space (EDN1)
proteinaceous extracellular matrix (MMP1) cell-cell signaling (EDN1) cytoplasm (EDN1)
EDN1 (Homo sapiens)
MMP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 35 75.56 Quite High
cytokine 3 5.00 Very Low Very Low Very Low
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 3 94.76 High High
Osteoarthritis 36 75.56 Quite High
Apoptosis 14 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 3 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Osteoporosis 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Rheumatic Diseases 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Results show that ET-1 greatly increased MMP-1 and MMP-13 production, iNOS expression and NO release.
ET-1 Neg (NO) Positive_regulation (increased) of Localization (release) of MMP-1
1) Confidence 0.17 Published 2005 Journal Arthritis Res Ther Section Abstract Doc Link PMC1065327 Disease Relevance 0.31 Pain Relevance 0.07

General Comments

This test has worked.

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