INT182298

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Context Info
Confidence 0.15
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.25
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (COL5A2) molecular_function (COL5A2)
Anatomy Link Frequency
cartilage 2
COL5A2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 35 99.60 Very High Very High Very High
Pain 1 52.40 Quite High
rheumatoid arthritis 3 48.16 Quite Low
Inflammation 5 39.04 Quite Low
cytokine 6 5.00 Very Low Very Low Very Low
Dismenorea 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
cOX1 1 5.00 Very Low Very Low Very Low
Calcium channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 36 99.60 Very High Very High Very High
Pain 1 52.40 Quite High
Rheumatoid Arthritis 3 48.16 Quite Low
INFLAMMATION 5 39.04 Quite Low
Disease 1 34.72 Quite Low
Apoptosis 14 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Stress 3 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Effect of thrombin treatment on hUtSMC collagen contractility
Regulation (Effect) of Positive_regulation (hUtSMC) of collagen
1) Confidence 0.15 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2645409 Disease Relevance 0 Pain Relevance 0
In OA cartilage, ET-1 is involved in cartilage catabolism through metalloprotease (MMP) regulation and the induction of type II collagen breakdown [2].
Regulation (involved) of Positive_regulation (induction) of collagen in cartilage associated with osteoarthritis
2) Confidence 0.01 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1065327 Disease Relevance 0.25 Pain Relevance 0.15

General Comments

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