INT18231

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Context Info
Confidence 0.14
First Reported 1988
Last Reported 1990
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.17
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (ADRA1D) extracellular region (HP) plasma membrane (ADRA1D)
cell-cell signaling (ADRA1D) DNA metabolic process (ADRA1D) signal transducer activity (ADRA1D)
ADRA1D (Homo sapiens)
HP (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 2 99.04 Very High Very High Very High
Dopamine 7 94.64 High High
Serotonin 1 89.08 High High
Clonidine 2 85.08 High High
agonist 1 80.08 Quite High
Neurotransmitter 2 75.92 Quite High
antagonist 2 70.96 Quite High
Disease Link Frequency Relevance Heat
Benign Prostatic Hypertrophy 2 100.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The affinity of doxazosin for alpha 1 binding sites in the prostate adenoma was approximately 100-fold greater than its affinity for alpha 2 binding sites.
alpha 1 Binding (affinity) of binding associated with benign prostatic hypertrophy
1) Confidence 0.14 Published 1990 Journal Prostate Section Abstract Doc Link 1968249 Disease Relevance 0.17 Pain Relevance 0.13
Risperidone displayed higher binding affinity than ritanserin and haloperidol for alpha-1 adrenergic (Ki = 0.8 nM), histamine-H1 (Ki = 2.23 nM) and alpha-2 adrenergic receptors (Ki = 7.54 nM).
alpha-1 Binding (affinity) of binding
2) Confidence 0.00 Published 1988 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 2460616 Disease Relevance 0 Pain Relevance 0.50

General Comments

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