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Context Info
Confidence 0.28
First Reported 2005
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.32
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (GLI2) cell proliferation (GLI2) nucleus (GLI2)
intracellular (GLI2) cilium (GLI2) cytoplasm (GLI2)
Anatomy Link Frequency
THP-1 2
GLI2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 10 99.16 Very High Very High Very High
rheumatoid arthritis 67 90.20 High High
Inflammatory response 3 64.44 Quite High
methotrexate 17 5.00 Very Low Very Low Very Low
Mechanotransduction 8 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
Leflunomide 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 14 99.16 Very High Very High Very High
Cancer 50 91.28 High High
Rheumatoid Arthritis 67 90.20 High High
Metastasis 23 83.76 Quite High
Osteoporosis 2 77.20 Quite High
Arthropathy 32 54.64 Quite High
Stress 2 54.40 Quite High
Bone Cancer 6 54.20 Quite High
Adhesions 2 51.92 Quite High
Apoptosis 27 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Gli2 and PTHrP expression did not increase for moduli above 1 GPa.
Neg (not) Positive_regulation (increase) of Gene_expression (expression) of Gli2
1) Confidence 0.28 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2981576 Disease Relevance 0.94 Pain Relevance 0
To assess the role of survivin in the inflammatory process, the human mononuclear cell line THP-1 was transfected with oligonucleotides targeting different regions of survivin mRNA.
Positive_regulation (transfected) of Gene_expression (transfected) of THP-1 in THP-1 associated with inflammation
2) Confidence 0.05 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1065333 Disease Relevance 0.37 Pain Relevance 0.16

General Comments

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