INT182374

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Context Info
Confidence 0.15
First Reported 2005
Last Reported 2006
Negated 1
Speculated 0
Reported most in Body
Documents 6
Total Number 9
Disease Relevance 1.88
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Lman1) vesicle-mediated transport (Lman1) Golgi apparatus (Lman1)
endoplasmic reticulum (Lman1)
Anatomy Link Frequency
vesicle 2
testis 1
nucleus 1
edge 1
neural 1
Lman1 (Mus musculus)
Pain Link Frequency Relevance Heat
isoflurane 5 43.88 Quite Low
nMDA receptor antagonist 5 27.00 Quite Low
nMDA receptor 25 20.52 Low Low
projection neuron 10 17.28 Low Low
cytokine 4 8.00 Low Low
tetrodotoxin 5 5.00 Very Low Very Low Very Low
sodium channel 5 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
medulla 5 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 170 99.84 Very High Very High Very High
Immunization 56 70.00 Quite High
Sprains And Strains 20 7.72 Low Low
Hematological Disease 4 5.00 Very Low Very Low Very Low
Body Weight 4 5.00 Very Low Very Low Very Low
Adhesions 4 5.00 Very Low Very Low Very Low
Hemorrhage 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results indicated that the present rat antisera specifically ­recognized mouse ERGIC-53 or c-Kit.


ERGIC-53 Binding (recognized) of
1) Confidence 0.15 Published 2006 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC1790970 Disease Relevance 0.16 Pain Relevance 0
Anti-­ERGIC-53 antisera recognized acinar cells in the sublingual gland, and anti-c-Kit antisera recognized spermatogenic and Leydig cells in the testis.
ERGIC-53 Binding (recognized) of in testis
2) Confidence 0.11 Published 2006 Journal Acta Histochemica et Cytochemica Section Abstract Doc Link PMC1790970 Disease Relevance 0.07 Pain Relevance 0
ERGIC-53 with its luminal domain binds glycoprotein ­products in the ER and with its cytosolic domain binds COPII and COPI, the vesicle-coating proteins involved in ER-Golgi antero- and retrograde transports, respectively [4].
ERGIC-53 Binding (binds) of in vesicle
3) Confidence 0.09 Published 2006 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC1790970 Disease Relevance 0 Pain Relevance 0
ERGIC-53 with its luminal domain binds glycoprotein ­products in the ER and with its cytosolic domain binds COPII and COPI, the vesicle-coating proteins involved in ER-Golgi antero- and retrograde transports, respectively [4].
ERGIC-53 Binding (binds) of in vesicle
4) Confidence 0.09 Published 2006 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC1790970 Disease Relevance 0 Pain Relevance 0
Regions immediately surrounding LMAN were also affected, and we cannot rule out an indirect contribution from the partial inactivation of these regions.
LMAN Binding (surrounding) of
5) Confidence 0.05 Published 2005 Journal PLoS Biology Section Body Doc Link PMC1069649 Disease Relevance 0.30 Pain Relevance 0
This observation implies that, in addition to slow neurotrophic effects, LMAN acts on RA rapidly to drive or control song variability, a necessary ingredient of reinforcement learning.
LMAN Binding (acts) of associated with rheumatoid arthritis
6) Confidence 0.05 Published 2005 Journal PLoS Biology Section Body Doc Link PMC1069649 Disease Relevance 0.26 Pain Relevance 0
m anterior to the edge of LMAN, the other in which the injections were approximately 200 ?
LMAN Binding (anterior) of in edge
7) Confidence 0.04 Published 2005 Journal PLoS Biology Section Body Doc Link PMC1069649 Disease Relevance 0.33 Pain Relevance 0
All injection sites were verified by histological examination and were found to be within the target nucleus (see Figure S1), except for TTX injections in LMAN in two birds: one in which the LMAN injection site in one hemisphere was found to be approximately 100 ?
LMAN Neg (except) Binding (birds) of in nucleus
8) Confidence 0.04 Published 2005 Journal PLoS Biology Section Body Doc Link PMC1069649 Disease Relevance 0.33 Pain Relevance 0
Chronic neural recordings in LMAN
LMAN Binding (recordings) of in neural
9) Confidence 0.04 Published 2005 Journal PLoS Biology Section Body Doc Link PMC1069649 Disease Relevance 0.42 Pain Relevance 0

General Comments

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