INT182375

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Context Info
Confidence 0.54
First Reported 2005
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 6
Total Number 8
Disease Relevance 2.86
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Lman1) vesicle-mediated transport (Lman1) Golgi apparatus (Lman1)
endoplasmic reticulum (Lman1)
Anatomy Link Frequency
nucleus 2
Lman1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 112 92.72 High High
agonist 4 39.92 Quite Low
isoflurane 4 19.60 Low Low
nMDA receptor antagonist 4 19.32 Low Low
nMDA receptor 20 12.84 Low Low
Inflammation 15 5.00 Very Low Very Low Very Low
chemokine 15 5.00 Very Low Very Low Very Low
Inflammatory response 9 5.00 Very Low Very Low Very Low
projection neuron 8 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Immunization 14 98.72 Very High Very High Very High
Infection 165 96.88 Very High Very High Very High
Rheumatoid Arthritis 136 92.92 High High
Sprains And Strains 185 85.56 High High
Disease 9 74.96 Quite High
Death 9 71.84 Quite High
Sepsis 21 71.44 Quite High
Genetic Predisposition To Disease 9 65.40 Quite High
INFLAMMATION 18 5.00 Very Low Very Low Very Low
Communicable Diseases 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A total of 10 genes (March3, Cep120, Chmp1b, Dcp2, Dtwd2, Isoc1, Lman1, Spire1, Tnfaip8, and Seh1l) mapping within our two significant QTLs were differentially expressed between S. aureus infected A/J and C57BL/6J mice.
Gene_expression (expressed) of Lman1
1) Confidence 0.54 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2932726 Disease Relevance 0.27 Pain Relevance 0
Ten genes (March3, Cep120, Chmp1b, Dcp2, Dtwd2, Isoc1, Lman1, Spire1, Tnfaip8, and Seh1l) mapped to the two significant QTLs and were differentially expressed between A/J and C57BL/6J.
Gene_expression (expressed) of Lman1
2) Confidence 0.47 Published 2010 Journal PLoS Pathogens Section Abstract Doc Link PMC2932726 Disease Relevance 0.90 Pain Relevance 0.12
Using real-time PCR, 6 of these 10 genes (Chmp1b, Dtwd2, Isoc1, Lman1, Tnfaip8, and Seh1l) showed significantly different expression levels between S. aureus-infected A/J and C57BL/6J.
Gene_expression (expression) of Lman1
3) Confidence 0.42 Published 2010 Journal PLoS Pathogens Section Abstract Doc Link PMC2932726 Disease Relevance 0.47 Pain Relevance 0.08
Using this method, we produced antisera against two mouse proteins: ERGIC-53 and c-Kit.
Gene_expression (produced) of ERGIC-53
4) Confidence 0.16 Published 2006 Journal Acta Histochemica et Cytochemica Section Abstract Doc Link PMC1790970 Disease Relevance 0.10 Pain Relevance 0
Thus, our results suggest that the loss of vocal plasticity following permanent lesions of LMAN may, in part at least, be due to the immediate loss of exploratory behavior.
Gene_expression (lesions) of LMAN
5) Confidence 0.08 Published 2005 Journal PLoS Biology Section Body Doc Link PMC1069649 Disease Relevance 0.24 Pain Relevance 0
Bilateral injections of TTX into MMAN, done in the same birds in which LMAN injections were previously made, had no significant effect on acoustic variability (Figure 2B).
Gene_expression (injections) of LMAN
6) Confidence 0.07 Published 2005 Journal PLoS Biology Section Body Doc Link PMC1069649 Disease Relevance 0.21 Pain Relevance 0
All injection sites were verified by histological examination and were found to be within the target nucleus (see Figure S1), except for TTX injections in LMAN in two birds: one in which the LMAN injection site in one hemisphere was found to be approximately 100 ?
Neg (except) Gene_expression (injections) of LMAN in nucleus
7) Confidence 0.07 Published 2005 Journal PLoS Biology Section Body Doc Link PMC1069649 Disease Relevance 0.34 Pain Relevance 0
All injection sites were verified by histological examination and were found to be within the target nucleus (see Figure S1), except for TTX injections in LMAN in two birds: one in which the LMAN injection site in one hemisphere was found to be approximately 100 ?
Gene_expression (injection) of LMAN in nucleus
8) Confidence 0.07 Published 2005 Journal PLoS Biology Section Body Doc Link PMC1069649 Disease Relevance 0.33 Pain Relevance 0

General Comments

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