INT182428

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Context Info
Confidence 0.02
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.43
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (NFYA) DNA binding (NFYA)
NFYA (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 2 20.48 Low Low
metalloproteinase 9 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 3 99.44 Very High Very High Very High
Contagious Ecthyma 1 93.04 High High
Apoptosis 18 84.80 Quite High
Aneuploidy 8 53.28 Quite High
Chromosomal Instability 4 52.64 Quite High
Cancer 96 50.08 Quite High
Ovarian Cancer 16 50.00 Quite Low
Carcinoma 4 48.72 Quite Low
Leukemia 2 44.72 Quite Low
Lymphatic System Cancer 2 43.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the mouse OGG1 gene also contains putative binding sites for NF-Y (position 2028–2040) and E2F (positions 967–974 and 231–240).
NF-Y Binding (binding) of
1) Confidence 0.02 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1072800 Disease Relevance 0.09 Pain Relevance 0
Furthermore, these investigators demonstrated that activation of p53 alone is sufficient to cause repression of securin by reducing the binding of the transcription factor NF-Y to its promoter.


NF-Y Binding (binding) of associated with repression
2) Confidence 0.01 Published 2008 Journal J Ovarian Res Section Body Doc Link PMC2584053 Disease Relevance 0.34 Pain Relevance 0

General Comments

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