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Context Info
Confidence 0.53
First Reported 1990
Last Reported 1990
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.49
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell-cell signaling (POMC, GNRH1) extracellular space (POMC, GNRH1) signal transduction (POMC, GNRH1)
extracellular region (POMC, GNRH1) small molecule metabolic process (POMC) cytoplasm (POMC)
Anatomy Link Frequency
pituitary 2
POMC (Homo sapiens)
GNRH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 1 99.76 Very High Very High Very High
Morphine 2 93.20 High High
Disease Link Frequency Relevance Heat
Stress 7 95.36 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Opioids, primarily beta-endorphin, originating through CRF-independent mechanisms in the brain or even the pituitary may also inhibit GnRH production.
beta-endorphin Spec (may) Negative_regulation (inhibit) of Gene_expression (production) of GnRH in pituitary associated with opioid
1) Confidence 0.53 Published 1990 Journal Int. J. Fertil. Section Abstract Doc Link 1968447 Disease Relevance 0.49 Pain Relevance 0.29

General Comments

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