INT18248

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Context Info
Confidence 0.15
First Reported 1990
Last Reported 1990
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.92
Pain Relevance 0.52

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signal transduction (CGA, GNRH1) extracellular region (CGA, GNRH1) cell-cell signaling (CGA, GNRH1)
extracellular space (GNRH1) small molecule metabolic process (CGA) cellular nitrogen compound metabolic process (CGA)
Anatomy Link Frequency
neurons 2
CGA (Homo sapiens)
GNRH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 2 99.04 Very High Very High Very High
Morphine 4 80.32 Quite High
Disease Link Frequency Relevance Heat
Stress 14 94.32 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Corticotropin-releasing factor (CRF) does interact with gonadotropin-releasing hormone (GnRH)-producing neurons, probably through an opioidergic pathway, suppressing gonadotropin secretion.
gonadotropin Binding (interact) of GnRH in neurons
1) Confidence 0.15 Published 1990 Journal Int. J. Fertil. Section Abstract Doc Link 1968447 Disease Relevance 0.46 Pain Relevance 0.26
Corticotropin-releasing factor (CRF) does interact with gonadotropin-releasing hormone (GnRH)-producing neurons, probably through an opioidergic pathway, suppressing gonadotropin secretion.
gonadotropin Binding (interact) of gonadotropin-releasing hormone in neurons
2) Confidence 0.15 Published 1990 Journal Int. J. Fertil. Section Abstract Doc Link 1968447 Disease Relevance 0.46 Pain Relevance 0.26

General Comments

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